2OSL

Crystal structure of Rituximab Fab in complex with an epitope peptide

Summary for 2OSL

• Entry DOI: 10.2210/pdb2osl/pdb
• Descriptor: light chain of the Rituximab Fab fragment,light chain of the Rituximab Fab fragment, heavy chain of the Rituximab Fab fragment,heavy chain of the Rituximab Fab fragment, B-lymphocyte antigen CD20, ... (4 entities in total)
• Functional Keywords: fab-peptide complex, rituximab, chimeric antibody, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 99328.43

Authors

Du, J.,Zhong, C.,Ding, J. (deposition date: 2007-02-06, release date: 2007-04-10, Last modification date: 2024-04-10)

• Primary citation: Du, J.,Wang, H.,Zhong, C.,Peng, B.,Zhang, M.,Li, B.,Huo, S.,Guo, Y.,Ding, J.; Structural basis for recognition of CD20 by therapeutic antibody Rituximab; J.Biol.Chem., 282:15073-15080, 2007; PubMed: 17395584; DOI: 10.1074/jbc.M701654200

Experimental method

X-RAY DIFFRACTION (2.6 Å)