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2OSL

Crystal structure of Rituximab Fab in complex with an epitope peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(L, B)
light chain of the Rituximab Fab fragment,light chain of the Rituximab Fab fragmentpolymer21323078.62Mus musculus (house mouse)
2B, D
(H, A)
heavy chain of the Rituximab Fab fragment,heavy chain of the Rituximab Fab fragmentpolymer22423733.52Mus musculus (house mouse)
3E, F
(P, Q)
B-lymphocyte antigen CD20polymer252852.12UniProt (P11836)Homo sapiensB-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1
4G, H, I, J, K...
(L, H, B, A, P...)
waterwater18.0212Chemie (HOH)
Sequence modifications
L, B: 1 - 106 (PDB: 2OSL)
L, B: 107 - 213 (PDB: 2OSL)
H, A: 1 - 121 (PDB: 2OSL)
H, A: 122 - 224 (PDB: 2OSL)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight99328.4
All*Total formula weight99328.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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