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PDB: 346 件
2DSD
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BU of 2dsd by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2QFY
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BU of 2qfy by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with a-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, Isocitrate dehydrogenase [NADP]
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
6KDY
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BU of 6kdy by Molmil
Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NAD.
分子名称: 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, HEXAETHYLENE GLYCOL, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Sun, P, Ding, J.
登録日2019-07-03
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
7VUX
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BU of 7vux by Molmil
Complex structure of PD1 and 609A-Fab
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X.
登録日2021-11-04
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.
Mabs, 14, 2022
3OPT
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BU of 3opt by Molmil
Crystal structure of the Rph1 catalytic core with a-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, DNA damage-responsive transcriptional repressor RPH1, NICKEL (II) ION
著者Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J.
登録日2010-09-02
公開日2010-12-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism
Biochem.J., 433, 2011
6KE3
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BU of 6ke3 by Molmil
Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Sun, P, Ding, J.
登録日2019-07-03
公開日2019-09-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
3OPW
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BU of 3opw by Molmil
Crystal Structure of the Rph1 catalytic core
分子名称: DNA damage-responsive transcriptional repressor RPH1
著者Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J.
登録日2010-09-02
公開日2010-12-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism
Biochem.J., 433, 2011
6KDF
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BU of 6kdf by Molmil
Crystal structure of the alpha beta heterodimer of human IDH3 in APO form.
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Ding, J.
登録日2019-07-02
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
7VKK
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BU of 7vkk by Molmil
Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION
著者Zhang, T, Ding, J.
登録日2021-09-30
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
3CXD
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BU of 3cxd by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide
分子名称: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
著者Du, J, Yang, H, Zhong, C, Ding, J.
登録日2008-04-24
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
2QFV
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BU of 2qfv by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+)
分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2QFX
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BU of 2qfx by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+)
分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ...
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2QUJ
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BU of 2quj by Molmil
Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP
分子名称: CHLORIDE ION, GLYCEROL, TRYPTOPHAN, ...
著者Shen, N, Ding, J.P.
登録日2007-08-05
公開日2008-04-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Nucleic Acids Res., 36, 2008
3DSF
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BU of 3dsf by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide
分子名称: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
著者Du, J, Zhong, C, Yang, H, Ding, J.
登録日2008-07-12
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
2QFW
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BU of 2qfw by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate
分子名称: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP]
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2HCR
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BU of 2hcr by Molmil
crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion
分子名称: ADENOSINE MONOPHOSPHATE, CADMIUM ION, Ribose-phosphate pyrophosphokinase I, ...
著者Li, S, Peng, B, Ding, J.
登録日2006-06-18
公開日2006-10-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
4H0N
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BU of 4h0n by Molmil
Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant
分子名称: CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J.
登録日2012-09-09
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Functional and structural characterization of DNMT2 from Spodoptera frugiperda.
J Mol Cell Biol, 5, 2013
1XTS
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BU of 1xts by Molmil
Structure of small GTPase human Rheb in complex with GTP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
1XTQ
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BU of 1xtq by Molmil
Structure of small GTPase human Rheb in complex with GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
1XTR
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BU of 1xtr by Molmil
Structure of small GTPase human Rheb in complex with GppNHp
分子名称: GLYCEROL, GTP-binding protein Rheb, MAGNESIUM ION, ...
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
2HTG
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BU of 2htg by Molmil
Structural and functional characterization of TM VII of the NHE1 isoform of the Na+/H+ exchanger
分子名称: NHE1 isoform of Na+/H+ exchanger 1
著者Rainey, J.K, Ding, J, Xu, C, Fliegel, L, Sykes, B.D.
登録日2006-07-25
公開日2006-08-08
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of transmembrane segment VII of the Na(+)/H(+) exchanger isoform 1
J.Biol.Chem., 281, 2006
1T0L
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BU of 1t0l by Molmil
Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+)
分子名称: CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
著者Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J.
登録日2004-04-10
公開日2004-06-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
4X9Z
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BU of 4x9z by Molmil
Dimeric conotoxin alphaD-GeXXA
分子名称: alphaD-conotoxin GeXXA from the venom of Conus generalis
著者Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C.
登録日2014-12-12
公開日2015-12-02
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
Sci Rep, 5, 2015
2DSB
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BU of 2dsb by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5
分子名称: ADP-sugar pyrophosphatase
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2DSC
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BU of 2dsc by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006

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