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PDB: 340 件

4FUW
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Crystal structure of Ego3 mutant
分子名称: Protein SLM4, SULFATE ION
著者Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J.
登録日2012-06-28
公開日2012-11-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
5GJS
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Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Wang, W, Zhang, T, Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
4FTX
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Crystal structure of Ego3 homodimer
分子名称: Protein SLM4, SUCCINIC ACID
著者Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J.
登録日2012-06-28
公開日2012-11-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
4ZB3
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Crystal structure of the apo AtNUDT7
分子名称: Nudix hydrolase 7, SULFATE ION
著者Tang, Q, Liu, C, Zhong, C, Ding, J.
登録日2015-04-14
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation.
Mol Plant, 8, 2015
5ZVB
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APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dT9)
分子名称: APEBEC3F/ssDNA-T9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*T)-3'), ...
著者Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y.
登録日2018-05-09
公開日2018-11-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
3CXD
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Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide
分子名称: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
著者Du, J, Yang, H, Zhong, C, Ding, J.
登録日2008-04-24
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
5ZVA
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APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9)
分子名称: APEBEC3F/ssDNA-C9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3'), ...
著者Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y.
登録日2018-05-09
公開日2018-11-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
5GJT
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Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ...
著者Wang, W, Zhang, T, Ding, J.
登録日2016-07-01
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
2HTG
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Structural and functional characterization of TM VII of the NHE1 isoform of the Na+/H+ exchanger
分子名称: NHE1 isoform of Na+/H+ exchanger 1
著者Rainey, J.K, Ding, J, Xu, C, Fliegel, L, Sykes, B.D.
登録日2006-07-25
公開日2006-08-08
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of transmembrane segment VII of the Na(+)/H(+) exchanger isoform 1
J.Biol.Chem., 281, 2006
3VPV
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Crystal Structure of Pseudomonas aeruginosa Tsi2
分子名称: Tse2 specific immunity protein 2
著者Wang, W, Ding, J, Wang, D.C.
登録日2012-03-13
公開日2012-03-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Pseudomonas aeruginosa Tsi2
To be Published
3F6G
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Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II
分子名称: Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ...
著者Zhang, P, Ma, J, Zhao, G, Ding, J.
登録日2008-11-06
公開日2009-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
2K3C
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Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger
分子名称: TMIX peptide
著者Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K.
登録日2008-05-01
公開日2008-06-03
最終更新日2020-02-19
実験手法SOLUTION NMR
主引用文献Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger.
J.Biol.Chem., 283, 2008
1T0L
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Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+)
分子名称: CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
著者Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J.
登録日2004-04-10
公開日2004-06-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
3JXE
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Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase in complex with TrpAMP
分子名称: SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Yang, B, Ding, J.
登録日2009-09-19
公開日2009-11-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
To be Published
3DSF
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BU of 3dsf by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide
分子名称: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
著者Du, J, Zhong, C, Yang, H, Ding, J.
登録日2008-07-12
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
2DR2
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BU of 2dr2 by Molmil
Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp)
分子名称: SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ...
著者Shen, N, Guo, L, Yang, B, Jin, Y, Ding, J.
登録日2006-06-05
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
Nucleic Acids Res., 34, 2006
7X9E
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Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide
分子名称: 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide
著者Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B.
登録日2022-03-15
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.
Nat Microbiol, 7, 2022
2HCR
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crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion
分子名称: ADENOSINE MONOPHOSPHATE, CADMIUM ION, Ribose-phosphate pyrophosphokinase I, ...
著者Li, S, Peng, B, Ding, J.
登録日2006-06-18
公開日2006-10-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
3E9G
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Crystal structure long-form (residue1-124) of Eaf3 chromo domain
分子名称: Chromatin modification-related protein EAF3
著者Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J.
登録日2008-08-22
公開日2008-11-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
5C74
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Structure of a novel protein arginine methyltransferase
分子名称: NICKEL (II) ION, Protein arginine N-methyltransferase SFM1, SULFATE ION
著者Lv, F, Ding, J.
登録日2015-06-24
公開日2016-01-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for Sfm1 functioning as a protein arginine methyltransferase.
Cell Discov, 1, 2015
4HKF
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Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA
分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION
著者Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J.
登録日2012-10-15
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
4ZA1
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Crystal Structure of NosA Involved in Nosiheptide Biosynthesis
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA
著者Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C.
登録日2015-04-13
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis
Sci Rep, 5, 2015
3F6H
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Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III
分子名称: Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION
著者Zhang, P, Ma, J, Zhao, G, Ding, J.
登録日2008-11-06
公開日2009-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
5EUE
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S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-methylisoxazole-3-carboxamide
分子名称: PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide
著者Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5EUD
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S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide
分子名称: PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide
著者Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016

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