4FUW
| Crystal structure of Ego3 mutant | 分子名称: | Protein SLM4, SULFATE ION | 著者 | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | 登録日 | 2012-06-28 | 公開日 | 2012-11-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
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5GJS
| Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Wang, W, Zhang, T, Ding, J. | 登録日 | 2016-07-01 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses Nat Commun, 7, 2016
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4FTX
| Crystal structure of Ego3 homodimer | 分子名称: | Protein SLM4, SUCCINIC ACID | 著者 | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | 登録日 | 2012-06-28 | 公開日 | 2012-11-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
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4ZB3
| Crystal structure of the apo AtNUDT7 | 分子名称: | Nudix hydrolase 7, SULFATE ION | 著者 | Tang, Q, Liu, C, Zhong, C, Ding, J. | 登録日 | 2015-04-14 | 公開日 | 2015-09-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation. Mol Plant, 8, 2015
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5ZVB
| APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dT9) | 分子名称: | APEBEC3F/ssDNA-T9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*T)-3'), ... | 著者 | Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y. | 登録日 | 2018-05-09 | 公開日 | 2018-11-21 | 最終更新日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA Chin.J.Chem., 36, 2018
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3CXD
| Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | 著者 | Du, J, Yang, H, Zhong, C, Ding, J. | 登録日 | 2008-04-24 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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5ZVA
| APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9) | 分子名称: | APEBEC3F/ssDNA-C9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3'), ... | 著者 | Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y. | 登録日 | 2018-05-09 | 公開日 | 2018-11-21 | 最終更新日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA Chin.J.Chem., 36, 2018
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5GJT
| Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ... | 著者 | Wang, W, Zhang, T, Ding, J. | 登録日 | 2016-07-01 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses Nat Commun, 7, 2016
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2HTG
| Structural and functional characterization of TM VII of the NHE1 isoform of the Na+/H+ exchanger | 分子名称: | NHE1 isoform of Na+/H+ exchanger 1 | 著者 | Rainey, J.K, Ding, J, Xu, C, Fliegel, L, Sykes, B.D. | 登録日 | 2006-07-25 | 公開日 | 2006-08-08 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional characterization of transmembrane segment VII of the Na(+)/H(+) exchanger isoform 1 J.Biol.Chem., 281, 2006
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3VPV
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3F6G
| Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II | 分子名称: | Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ... | 著者 | Zhang, P, Ma, J, Zhao, G, Ding, J. | 登録日 | 2008-11-06 | 公開日 | 2009-04-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans Biochem.J., 421, 2009
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2K3C
| Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger | 分子名称: | TMIX peptide | 著者 | Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K. | 登録日 | 2008-05-01 | 公開日 | 2008-06-03 | 最終更新日 | 2020-02-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. J.Biol.Chem., 283, 2008
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1T0L
| Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+) | 分子名称: | CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | 著者 | Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J. | 登録日 | 2004-04-10 | 公開日 | 2004-06-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity J.Biol.Chem., 279, 2004
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3JXE
| Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase in complex with TrpAMP | 分子名称: | SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | 著者 | Zhou, M, Dong, X, Zhong, C, Shen, N, Yang, B, Ding, J. | 登録日 | 2009-09-19 | 公開日 | 2009-11-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase To be Published
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3DSF
| Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | 著者 | Du, J, Zhong, C, Yang, H, Ding, J. | 登録日 | 2008-07-12 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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2DR2
| Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) | 分子名称: | SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ... | 著者 | Shen, N, Guo, L, Yang, B, Jin, Y, Ding, J. | 登録日 | 2006-06-05 | 公開日 | 2006-07-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity Nucleic Acids Res., 34, 2006
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7X9E
| Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide | 分子名称: | 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide | 著者 | Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol, 7, 2022
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2HCR
| crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion | 分子名称: | ADENOSINE MONOPHOSPHATE, CADMIUM ION, Ribose-phosphate pyrophosphokinase I, ... | 著者 | Li, S, Peng, B, Ding, J. | 登録日 | 2006-06-18 | 公開日 | 2006-10-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site Biochem.J., 401, 2007
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3E9G
| Crystal structure long-form (residue1-124) of Eaf3 chromo domain | 分子名称: | Chromatin modification-related protein EAF3 | 著者 | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | 登録日 | 2008-08-22 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36 J.Biol.Chem., 283, 2008
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5C74
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4HKF
| Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION | 著者 | Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J. | 登録日 | 2012-10-15 | 公開日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin Cell Res., 22, 2012
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4ZA1
| Crystal Structure of NosA Involved in Nosiheptide Biosynthesis | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA | 著者 | Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C. | 登録日 | 2015-04-13 | 公開日 | 2015-08-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis Sci Rep, 5, 2015
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3F6H
| Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III | 分子名称: | Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION | 著者 | Zhang, P, Ma, J, Zhao, G, Ding, J. | 登録日 | 2008-11-06 | 公開日 | 2009-04-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans Biochem.J., 421, 2009
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5EUE
| S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-methylisoxazole-3-carboxamide | 分子名称: | PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide | 著者 | Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M. | 登録日 | 2015-11-18 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Creation of a S1P Lyase bacterial surrogate for structure-based drug design. Bioorg.Med.Chem.Lett., 26, 2016
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5EUD
| S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide | 分子名称: | PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide | 著者 | Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M. | 登録日 | 2015-11-18 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Creation of a S1P Lyase bacterial surrogate for structure-based drug design. Bioorg.Med.Chem.Lett., 26, 2016
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