2HCR

crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion

Summary for 2HCR

• Entry DOI: 10.2210/pdb2hcr/pdb
• Related: 2H06
• Descriptor: Ribose-phosphate pyrophosphokinase I, SULFATE ION, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: prs1, prpp synthetase 1, phosphoribosyl pyrophosphate 1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 73396.39

Authors

Li, S.,Peng, B.,Ding, J. (deposition date: 2006-06-18, release date: 2006-10-24, Last modification date: 2023-10-25)

• Primary citation: Li, S.,Lu, Y.,Peng, B.,Ding, J.; Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site; Biochem.J., 401:39-47, 2007; PubMed: 16939420; DOI: 10.1042/BJ20061066

Experimental method

X-RAY DIFFRACTION (2.2 Å)