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PDB: 346 件
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
4LAL
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BU of 4lal by Molmil
Crystal structure of Cordyceps militaris IDCase D323A mutant in complex with 5-carboxyl-uracil
分子名称: 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, HEXAETHYLENE GLYCOL, Uracil-5-carboxylate decarboxylase, ...
著者Xu, S, Li, W, Zhu, J, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAM
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BU of 4lam by Molmil
Crystal structure of Cordyceps militaris IDCase D323N mutant in complex with 5-carboxyl-uracil
分子名称: 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, HEXAETHYLENE GLYCOL, Uracil-5-carboxylate decarboxylase, ...
著者Xu, S, Li, W, Zhu, J, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
1T05
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BU of 1t05 by Molmil
HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate
分子名称: GLYCEROL, MAGNESIUM ION, POL polyprotein, ...
著者Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E.
登録日2004-04-07
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Nat.Struct.Mol.Biol., 11, 2004
5Y7L
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BU of 5y7l by Molmil
Solution structure of Hbeta4 extracellular loop of BK potassium channel
分子名称: Calcium-activated potassium channel subunit beta-4
著者Wang, Y, Lan, W, Ding, J, Cao, C.
登録日2017-08-17
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity.
Sci Rep, 8, 2018
7CY8
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BU of 7cy8 by Molmil
Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C
分子名称: 1,2-ETHANEDIOL, ASCORBIC ACID, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), ...
著者Li, W, Zhang, T, Sun, M, Ding, J.
登録日2020-09-03
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
5GRE
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BU of 5gre by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5YVT
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BU of 5yvt by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Ma, T, Ding, J.
登録日2017-11-27
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into the inhibitory mechanisms of NADH on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 8, 2018
5GRI
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BU of 5gri by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and citrate
分子名称: CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
4FUW
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BU of 4fuw by Molmil
Crystal structure of Ego3 mutant
分子名称: Protein SLM4, SULFATE ION
著者Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J.
登録日2012-06-28
公開日2012-11-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
3RPP
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BU of 3rpp by Molmil
Crystal structure of human kappa class glutathione transferase in apo form
分子名称: Glutathione S-transferase kappa 1
著者Wang, B, Peng, Y, Zhang, T, Ding, J.
登録日2011-04-27
公開日2011-07-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
2QUK
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BU of 2quk by Molmil
Crystal structures of human tryptophanyl-tRNA synthetase in complex with ATP(putative)
分子名称: Tryptophanyl-tRNA synthetase
著者Shen, N, Ding, J.P.
登録日2007-08-06
公開日2008-04-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Nucleic Acids Res., 36, 2008
4LAN
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BU of 4lan by Molmil
Crystal structure of Cordyceps militaris IDCase H195A mutant
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Li, W, Zhu, J, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAK
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BU of 4lak by Molmil
Crystal structure of Cordyceps militaris IDCase D323N mutant in apo form
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Li, W, Zhu, J, Wang, R, Li, Z, Xu, G.L, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
7CY5
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BU of 7cy5 by Molmil
Crystal Structure of CMD1 in complex with vitamin C
分子名称: ASCORBIC ACID, CITRIC ACID, FE (III) ION, ...
著者Li, W, Zhang, T, Sun, M, Ding, J.
登録日2020-09-03
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
4LAO
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BU of 4lao by Molmil
Crystal structure of Cordyceps militaris IDCase H195A mutant (Zn)
分子名称: Cordyceps militaris IDCase, DI(HYDROXYETHYL)ETHER, ZINC ION
著者Xu, S, Li, W, Zhu, J, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
7CY4
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BU of 7cy4 by Molmil
Crystal Structure of CMD1 in apo form
分子名称: CITRIC ACID, FE (III) ION, Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1
著者Li, W, Zhang, T, Sun, M, Ding, J.
登録日2020-09-03
公開日2020-12-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
3SPD
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BU of 3spd by Molmil
Crystal structure of aprataxin ortholog Hnt3 in complex with DNA
分子名称: Aprataxin-like protein, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), ...
著者Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D.
登録日2011-07-01
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.912 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
4N3Y
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BU of 4n3y by Molmil
Crystal structure of Rabex-5CC and Rabaptin-5C21 complex
分子名称: Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor
著者Zhang, Z, Zhang, T, Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
3SPL
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BU of 3spl by Molmil
Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin-like protein, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ...
著者Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D.
登録日2011-07-02
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
7CE3
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BU of 7ce3 by Molmil
Crystal structure of human IDH3 holoenzyme in APO form.
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, ...
著者Sun, P.K, Ding, J.P.
登録日2020-06-21
公開日2021-01-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.472 Å)
主引用文献Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase.
Cell Discov, 6, 2020
4HKF
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BU of 4hkf by Molmil
Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA
分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION
著者Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J.
登録日2012-10-15
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
3MAP
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BU of 3map by Molmil
Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate
分子名称: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yang, B, Peng, Y, Ding, J.
登録日2010-03-24
公開日2010-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
3DOF
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BU of 3dof by Molmil
Complex of ARL2 and BART, Crystal Form 2
分子名称: ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, T, Li, S, Ding, J.
登録日2008-07-04
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector
Structure, 17, 2009

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