4O0W
| |
4O0U
| |
7WR1
| P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain | 分子名称: | Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
|
|
7WR4
| Crystal structure of OspC3-calmodulin-caspase-4 complex | 分子名称: | Calmodulin-1, Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
|
|
7WR6
| Crystal structure of ADP-riboxanated caspase-4 in complex with Af1521 | 分子名称: | ADP-ribose glycohydrolase AF_1521, Caspase-4, [[(3~{a}~{S},5~{R},6~{R},6~{a}~{R})-2-azanylidene-3-[(4~{R})-4-azanyl-5-oxidanylidene-pentyl]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxazol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
|
|
7WR0
| P32 of caspase-4 C258A mutant | 分子名称: | Caspase-4 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
|
|
7WR2
| |
7WR5
| Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+ | 分子名称: | Calmodulin-1, Caspase-4, OspC3, ... | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
|
|
6KDY
| |
4ZA1
| Crystal Structure of NosA Involved in Nosiheptide Biosynthesis | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA | 著者 | Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C. | 登録日 | 2015-04-13 | 公開日 | 2015-08-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis Sci Rep, 5, 2015
|
|
6KE3
| |
6KDF
| |
3EO9
| Crystal structure the Fab fragment of Efalizumab | 分子名称: | Efalizumab Fab fragment, heavy chain, light chain | 著者 | Li, S, Ding, J. | 登録日 | 2008-09-26 | 公開日 | 2009-04-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5C3O
| Crystal structure of the C-terminal truncated Neurospora crassa T7H (NcT7HdeltaC) in apo form | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Thymine dioxygenase | 著者 | Li, W, Zhang, T, Ding, J. | 登録日 | 2015-06-17 | 公開日 | 2015-10-21 | 最終更新日 | 2015-12-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi Nucleic Acids Res., 43, 2015
|
|
4QXA
| Crystal structure of the Rab9A-RUTBC2 RBD complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-9A, ... | 著者 | Zhang, Z, Wang, S, Ding, J. | 登録日 | 2014-07-19 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2. Structure, 22, 2014
|
|
4FTX
| Crystal structure of Ego3 homodimer | 分子名称: | Protein SLM4, SUCCINIC ACID | 著者 | Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. | 登録日 | 2012-06-28 | 公開日 | 2012-11-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
|
|
6JWP
| crystal structure of EGOC | 分子名称: | Ego2, GTP-binding protein GTR1, GTP-binding protein GTR2, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2019-04-21 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases. Sci Adv, 5, 2019
|
|
4N3Y
| |
6KDE
| |
6LPX
| Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG) | 分子名称: | 2-OXOGLUTARIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | 著者 | Yang, J, Zhu, H, Ding, J. | 登録日 | 2020-01-12 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021
|
|
6LPP
| Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate (D-2-HG) | 分子名称: | (2R)-2-hydroxypentanedioic acid, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | 著者 | Yang, J, Zhu, H, Ding, J. | 登録日 | 2020-01-12 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021
|
|
6LPT
| Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-lactate (D-LAC) | 分子名称: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Yang, J, Zhu, H, Ding, J. | 登録日 | 2020-01-12 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.621 Å) | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021
|
|
4Q9U
| Crystal structure of the Rab5, Rabex-5delta and Rabaptin-5C21 complex | 分子名称: | Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A | 著者 | Zhang, Z, Zhang, T, Ding, J. | 登録日 | 2014-05-01 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.618 Å) | 主引用文献 | Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5 Elife, 3, 2014
|
|
2MYJ
| |
6JLQ
| Crystal structure of human USP46-WDR48-WDR20 complex | 分子名称: | GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ... | 著者 | Zhu, H, Zhang, T, Ding, J. | 登録日 | 2019-03-06 | 公開日 | 2019-07-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | 主引用文献 | Structural insights into the activation of USP46 by WDR48 and WDR20. Cell Discov, 5, 2019
|
|