2QUK
Crystal structures of human tryptophanyl-tRNA synthetase in complex with ATP(putative)
Summary for 2QUK
| Entry DOI | 10.2210/pdb2quk/pdb |
| Related | 1O5T 2AKE |
| Descriptor | Tryptophanyl-tRNA synthetase (2 entities in total) |
| Functional Keywords | aminoacyl-trna synthetase, rossmann fold, induced-fit mechnism, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P23381 |
| Total number of polymer chains | 1 |
| Total formula weight | 54060.11 |
| Authors | Shen, N.,Ding, J.P. (deposition date: 2007-08-06, release date: 2008-04-29, Last modification date: 2023-10-25) |
| Primary citation | Shen, N.,Zhou, M.,Yang, B.,Yu, Y.,Dong, X.,Ding, J. Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states Nucleic Acids Res., 36:1288-1299, 2008 Cited by PubMed: 18180246DOI: 10.1093/nar/gkm1153 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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