7CE3

Crystal structure of human IDH3 holoenzyme in APO form.

Summary for 7CE3

Entry DOI	10.2210/pdb7ce3/pdb
Descriptor	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (3 entities in total)
Functional Keywords	idh3, nad-idh, nad dependent isocitrate dehydrogenase, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	158399.11
Authors	Sun, P.K.,Ding, J.P. (deposition date: 2020-06-21, release date: 2021-01-06, Last modification date: 2023-11-29)
Primary citation	Sun, P.,Liu, Y.,Ma, T.,Ding, J. Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase. Cell Discov, 6:94-94, 2020 Cited by PubMed: 33349631 DOI: 10.1038/s41421-020-00220-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.472 Å)

Structure validation