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PDB: 346 results

8GRG
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BU of 8grg by Molmil
Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3
Descriptor: Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
Authors:Sun, P, Chen, X, Ding, J.
Deposit date:2022-09-01
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRH
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BU of 8grh by Molmil
Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT
Descriptor: CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ...
Authors:Sun, P, Chen, X, Ding, J.
Deposit date:2022-09-01
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRU
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BU of 8gru by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca
Descriptor: CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ...
Authors:Sun, P, Chen, X, Ding, J.
Deposit date:2022-09-02
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
3W8I
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Crystal structure of CCM3 in complex with the C-terminal regulatory domain of MST4
Descriptor: Programmed cell death protein 10, Serine/threonine-protein kinase MST4
Authors:Xu, X, Wang, D.C, Ding, J.
Deposit date:2013-03-13
Release date:2013-07-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
3W8H
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BU of 3w8h by Molmil
Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25
Descriptor: Programmed cell death protein 10, SULFATE ION, Serine/threonine-protein kinase 25
Authors:Xu, X, Wang, D.C, Ding, J.
Deposit date:2013-03-13
Release date:2013-07-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.426 Å)
Cite:Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
8GS5
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BU of 8gs5 by Molmil
Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form
Descriptor: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ...
Authors:Sun, P, Chen, X, Ding, J.
Deposit date:2022-09-04
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4.486 Å)
Cite:Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GTK
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BU of 8gtk by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex
Descriptor: GSDMB isoform-1, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Zhong, X, Hou, Y.J, Ding, J.
Deposit date:2022-09-08
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTJ
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BU of 8gtj by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
Descriptor: Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Zhong, X, Hou, Y.J, Ding, J.
Deposit date:2022-09-08
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTN
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BU of 8gtn by Molmil
Cryo-EM structure of the gasdermin B pore
Descriptor: Isoform 4 of Gasdermin-B
Authors:Hou, Y.J, Cheng, H, Ding, J.
Deposit date:2022-09-08
Release date:2023-04-12
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
4ZB3
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BU of 4zb3 by Molmil
Crystal structure of the apo AtNUDT7
Descriptor: Nudix hydrolase 7, SULFATE ION
Authors:Tang, Q, Liu, C, Zhong, C, Ding, J.
Deposit date:2015-04-14
Release date:2015-09-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation.
Mol Plant, 8, 2015
2F5J
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BU of 2f5j by Molmil
Crystal structure of MRG domain from human MRG15
Descriptor: Mortality factor 4-like protein 1
Authors:Zhang, P, Du, J, Ding, J.
Deposit date:2005-11-26
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006
2F5K
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BU of 2f5k by Molmil
Crystal structure of the chromo domain of human MRG15
Descriptor: Mortality factor 4-like protein 1
Authors:Zhang, P, Du, J, Ding, J.
Deposit date:2005-11-26
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
2DSC
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BU of 2dsc by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-sugar pyrophosphatase, MAGNESIUM ION
Authors:Zha, M, Zhong, C, Ding, J.
Deposit date:2006-06-28
Release date:2006-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2DSD
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BU of 2dsd by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP
Descriptor: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION
Authors:Zha, M, Zhong, C, Ding, J.
Deposit date:2006-06-28
Release date:2006-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2H06
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BU of 2h06 by Molmil
Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Descriptor: Ribose-phosphate pyrophosphokinase I, SULFATE ION
Authors:Li, S, Peng, B, Ding, J.
Deposit date:2006-05-14
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
4XPM
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BU of 4xpm by Molmil
Crystal structure of EGO-TC
Descriptor: Protein MEH1, Protein SLM4, Uncharacterized protein YCR075W-A
Authors:Powis, K, Zhang, T, De Virgilio, C, Ding, J.
Deposit date:2015-01-17
Release date:2015-08-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling.
Cell Res., 25, 2015
1O5T
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BU of 1o5t by Molmil
Crystal structure of the aminoacylation catalytic fragment of human tryptophanyl-tRNA synthetase
Descriptor: Tryptophanyl-tRNA synthetase
Authors:Yu, Y, Liu, Y, Shen, N, Xu, X, Jia, J, Jin, Y, Arnold, E, Ding, J.
Deposit date:2003-10-05
Release date:2004-07-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment
J.BIOL.CHEM., 279, 2004
8H68
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BU of 8h68 by Molmil
Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Shi, Y, Ding, J, Yang, H.
Deposit date:2022-10-16
Release date:2023-02-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Caenorhabditis elegans NMAD-1 functions as a demethylase for actin.
J Mol Cell Biol, 15, 2023
7VKK
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BU of 7vkk by Molmil
Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION
Authors:Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKR
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BU of 7vkr by Molmil
Crystal structure of D. melanogaster SAMTOR in complex with SAM
Descriptor: CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKQ
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BU of 7vkq by Molmil
Crystal structure of D. melanogaster SAMTOR in the SAH bound form
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
5H4B
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BU of 5h4b by Molmil
Crystal structure of Cbln4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-4
Authors:Zhong, C, Shen, J, Zhang, H, Ding, J.
Deposit date:2016-10-31
Release date:2017-09-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
4ZA1
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BU of 4za1 by Molmil
Crystal Structure of NosA Involved in Nosiheptide Biosynthesis
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA
Authors:Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C.
Deposit date:2015-04-13
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis
Sci Rep, 5, 2015
1WAV
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BU of 1wav by Molmil
CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN
Descriptor: INSULIN, PHENOL, ZINC ION
Authors:Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L.
Deposit date:1996-02-28
Release date:1997-02-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular replacement study on form-B monoclinic crystal of insulin.
Sci.China, Ser.C: Life Sci., 39, 1996
2DR2
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BU of 2dr2 by Molmil
Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp)
Descriptor: SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ...
Authors:Shen, N, Guo, L, Yang, B, Jin, Y, Ding, J.
Deposit date:2006-06-05
Release date:2006-07-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
Nucleic Acids Res., 34, 2006

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