8GTN

Cryo-EM structure of the gasdermin B pore

This is a non-PDB format compatible entry.

Summary for 8GTN

• Entry DOI: 10.2210/pdb8gtn/pdb
• EMDB information: 34258
• Descriptor: Isoform 4 of Gasdermin-B (1 entity in total)
• Functional Keywords: pyroptosis, pore-forming, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 27
• Total formula weight: 772975.04

Authors

Hou, Y.J.,Cheng, H.,Ding, J. (deposition date: 2022-09-08, release date: 2023-04-12, Last modification date: 2023-05-03)

• Primary citation: Zhong, X.,Zeng, H.,Zhou, Z.,Su, Y.,Cheng, H.,Hou, Y.,She, Y.,Feng, N.,Wang, J.,Shao, F.,Ding, J.; Structural mechanisms for regulation of GSDMB pore-forming activity.; Nature, 616:598-605, 2023; PubMed: 36991125; DOI: 10.1038/s41586-023-05872-5

Experimental method

ELECTRON MICROSCOPY (3.17 Å)