7CQ1
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7CJW
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![BU of 7cjw by Molmil](/molmil-images/mine/7cjw) | Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment | 分子名称: | Monomeric Human Cu,Zn Superoxide dismutase | 著者 | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | 登録日 | 2020-07-14 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel. J.Phys.Chem.B, 125, 2021
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7DL2
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![BU of 7dl2 by Molmil](/molmil-images/mine/7dl2) | Cryo-EM structure of human TSC complex | 分子名称: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | 著者 | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | 登録日 | 2020-11-25 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into TSC complex assembly and GAP activity on Rheb. Nat Commun, 12, 2021
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5OVF
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![BU of 5ovf by Molmil](/molmil-images/mine/5ovf) | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 17 | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[3-(1~{H}-pyrazol-4-yl)phenyl]ethyl]quinazolin-4-amine, Son of sevenless homolog 1 | 著者 | Hillig, R.C, Sautier, B, Schroeder, J, Moosmayer, D, Hilpmann, A, Stegmann, C.M, Briem, H, Boemer, U, Weiske, J, Badock, V, Petersen, K, Kahmann, J, Wegener, D, Bohnke, N, Eis, K, Graham, K, Wortmann, L, von Nussbaum, F, Bader, B. | 登録日 | 2017-08-28 | 公開日 | 2019-02-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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7D4A
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![BU of 7d4a by Molmil](/molmil-images/mine/7d4a) | The Crystal Structure of human JMJD2A Tudor domain from Biortus | 分子名称: | Lysine-specific demethylase 4A, SULFATE ION | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Ju, C, Bao, X, Zhu, B. | 登録日 | 2020-09-23 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | The Crystal Structure of human JMJD2A from Biortus. To Be Published
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5OX8
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![BU of 5ox8 by Molmil](/molmil-images/mine/5ox8) | Structure of Enhanced Cyan Fluorescent Protein at pH 5.0 | 分子名称: | CHLORIDE ION, Green fluorescent protein | 著者 | Gotthard, G, von Stetten, D, Clavel, D, Noirclerc-Savoye, M, Royant, A. | 登録日 | 2017-09-06 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Chromophore Isomer Stabilization Is Critical to the Efficient Fluorescence of Cyan Fluorescent Proteins. Biochemistry, 56, 2017
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7DSF
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![BU of 7dsf by Molmil](/molmil-images/mine/7dsf) | The Crystal Structure of human SPR from Biortus. | 分子名称: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Meng, Q, Zhang, B, Huang, Y. | 登録日 | 2020-12-31 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structure of human SPR from Biortus. To Be Published
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7DS7
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![BU of 7ds7 by Molmil](/molmil-images/mine/7ds7) | The Crystal Structure of Leaf-branch compost cutinase from Biortus. | 分子名称: | CITRIC ACID, GLYCEROL, IMIDAZOLE, ... | 著者 | Wang, F, Lv, Z, Cheng, W, Lin, D, Chu, F, Xu, X, Tan, J. | 登録日 | 2020-12-30 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Crystal Structure of Leaf-branch compost cutinase from Biortus. To Be Published
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7D2C
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![BU of 7d2c by Molmil](/molmil-images/mine/7d2c) | The Crystal Structure of human PARP14 from Biortus. | 分子名称: | CHLORIDE ION, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP14 | 著者 | Wang, F, Miao, Q, Lv, Z, Cheng, W, Lin, D, Xu, X, Tan, J. | 登録日 | 2020-09-16 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | The Crystal Structure of human PARP14 from Biortus. To Be Published
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7DFP
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![BU of 7dfp by Molmil](/molmil-images/mine/7dfp) | Human dopamine D2 receptor in complex with spiperone | 分子名称: | 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, D(2) dopamine receptor,Soluble cytochrome b562, FabH, ... | 著者 | Im, D, Shimamura, T, Iwata, S. | 登録日 | 2020-11-09 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone. Nat Commun, 11, 2020
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7DNO
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![BU of 7dno by Molmil](/molmil-images/mine/7dno) | Characterization of Peptide Ligands Against WDR5 Isolated Using Phage Display Technique | 分子名称: | CYS-ARG-THR-LEU-PRO-PHE, WD repeat-containing protein 5 | 著者 | Cao, J, Cao, D, Xiong, B, Li, Y, Fan, T. | 登録日 | 2020-12-10 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5. Molecules, 26, 2021
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5OVE
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![BU of 5ove by Molmil](/molmil-images/mine/5ove) | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 1 | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-~{N}-[(1~{R})-1-naphthalen-1-ylethyl]quinazolin-4-amine, Son of sevenless homolog 1 | 著者 | Hillig, R.C, Sautier, B, Schroeder, J, Moosmayer, D, Hilpmann, A, Stegmann, C.M, Briem, H, Boemer, U, Weiske, J, Badock, V, Petersen, K, Kahmann, J, Wegener, D, Bohnke, N, Eis, K, Graham, K, Wortmann, L, von Nussbaum, F, Bader, B. | 登録日 | 2017-08-28 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5OXB
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![BU of 5oxb by Molmil](/molmil-images/mine/5oxb) | Structure of blue-light irradiated Cerulean | 分子名称: | Green fluorescent protein | 著者 | Gotthard, G, von Stetten, D, Clavel, D, Noirclerc-Savoye, M, Royant, A. | 登録日 | 2017-09-06 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Chromophore Isomer Stabilization Is Critical to the Efficient Fluorescence of Cyan Fluorescent Proteins. Biochemistry, 56, 2017
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7DLA
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7D35
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![BU of 7d35 by Molmil](/molmil-images/mine/7d35) | Human LC8 bound to ebola virus VP35(67-76) | 分子名称: | Dynein light chain 1, cytoplasmic, Peptide from Polymerase cofactor VP35 | 著者 | Ku, B, Lim, D. | 登録日 | 2020-09-18 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Crystal structure of human LC8 bound to a peptide from Ebola virus VP35. J.Microbiol, 59, 2021
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7DA4
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![BU of 7da4 by Molmil](/molmil-images/mine/7da4) | Cryo-EM structure of amyloid fibril formed by human RIPK3 | 分子名称: | Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Zhao, K, Ma, Y.Y, Sun, Y.P, Li, D, Liu, C. | 登録日 | 2020-10-14 | 公開日 | 2021-04-28 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | 主引用文献 | The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proc.Natl.Acad.Sci.USA, 118, 2021
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7D73
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![BU of 7d73 by Molmil](/molmil-images/mine/7d73) | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | 分子名称: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, ... | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | 登録日 | 2020-10-02 | 公開日 | 2021-05-05 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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7D72
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![BU of 7d72 by Molmil](/molmil-images/mine/7d72) | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | 分子名称: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, Mannose-1-phosphate guanyltransferase alpha, ... | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | 登録日 | 2020-10-02 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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5EQQ
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![BU of 5eqq by Molmil](/molmil-images/mine/5eqq) | Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue) | 分子名称: | NS3 protease, SULFATE ION, ZINC ION, ... | 著者 | Soumana, D, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Aydin, C, Schiffer, C.A. | 登録日 | 2015-11-13 | 公開日 | 2016-01-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172. Acs Chem.Biol., 11, 2016
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7D74
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![BU of 7d74 by Molmil](/molmil-images/mine/7d74) | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, Mannose-1-phosphate guanyltransferase beta | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, cai, X, Mo, X, Gao, N, Jia, D. | 登録日 | 2020-10-02 | 公開日 | 2021-05-19 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
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7DRT
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![BU of 7drt by Molmil](/molmil-images/mine/7drt) | Human Wntless in complex with Wnt3a | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhong, Q, Zhao, Y, Ye, F, Xiao, Z, Huang, G, Zhang, Y, Lu, P, Xu, W, Zhou, Q, Ma, D. | 登録日 | 2020-12-29 | 公開日 | 2021-07-14 | 最終更新日 | 2021-09-08 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Cryo-EM structure of human Wntless in complex with Wnt3a. Nat Commun, 12, 2021
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7D7E
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![BU of 7d7e by Molmil](/molmil-images/mine/7d7e) | Structure of PKD1L3-CTD/PKD2L1 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | 著者 | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
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7CZ0
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![BU of 7cz0 by Molmil](/molmil-images/mine/7cz0) | Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb92) | 分子名称: | ACETATE ION, CACODYLATE ION, CACODYLIC ACID, ... | 著者 | Cai, H, Yao, H, Li, T, Hutter, C, Tang, Y, Li, Y, Seeger, M, Li, D. | 登録日 | 2020-09-06 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | An improved fluorescent protein tag and its nanobodies for membrane protein expression, stability assay, and purification To Be Published
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7D6W
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![BU of 7d6w by Molmil](/molmil-images/mine/7d6w) | Crystal structure of Phycocyanin from Synechococcus sp. R42DM | 分子名称: | PHYCOCYANOBILIN, Phycocyanin alpha subunit, Phycocyanin beta subunit | 著者 | Patel, S.N, Sonani, R.R, Chaubey, M.G, Singh, N.K, Kumar, V, Madamwar, D. | 登録日 | 2020-10-02 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of Synechococcus phycocyanin: implications of light-harvesting and antioxidant properties. 3 Biotech, 13, 2023
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7DNU
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![BU of 7dnu by Molmil](/molmil-images/mine/7dnu) | mRNA-decapping enzyme g5Rp with inhibitor insp6 complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, mRNA-decapping protein g5R | 著者 | Yang, Y, Chen, C, Li, L, Li, X.H, Su, D. | 登録日 | 2020-12-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Structural Insight into Molecular Inhibitory Mechanism of InsP 6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. J.Virol., 96, 2022
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