7D72
Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose
Summary for 7D72
Entry DOI | 10.2210/pdb7d72/pdb |
EMDB information | 30599 |
Descriptor | Mannose-1-phosphate guanyltransferase beta, Mannose-1-phosphate guanyltransferase alpha, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... (5 entities in total) |
Functional Keywords | gmppa, gmppb, gdp-mannose homeostasis, cell cycle, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 511731.38 |
Authors | |
Primary citation | Zheng, L.,Liu, Z.,Wang, Y.,Yang, F.,Wang, J.,Huang, W.,Qin, J.,Tian, M.,Cai, X.,Liu, X.,Mo, X.,Gao, N.,Jia, D. Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28:1-12, 2021 Cited by PubMed: 33986552DOI: 10.1038/s41594-021-00591-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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