7D72
Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H, I... (K, I, E, F, G...) | Mannose-1-phosphate guanyltransferase beta | polymer | 360 | 39878.3 | 8 | UniProt (Q9Y5P6) Pfam (PF00483) Pfam (PF00132) | Homo sapiens (Human) | GDP-mannose pyrophosphorylase B,GTP-mannose-1-phosphate guanylyltransferase beta |
| 2 | C, D, E, F (A, B, C, D) | Mannose-1-phosphate guanyltransferase alpha | polymer | 420 | 46342.0 | 4 | UniProt (Q96IJ6) Pfam (PF00483) Pfam (PF00132) | Homo sapiens (Human) | GDP-mannose pyrophosphorylase A,GMPP-alpha,GTP-mannose-1-phosphate guanylyltransferase alpha |
| 3 | AA, M, N, O, P... (L, K, I, A, B...) | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE | non-polymer | 605.3 | 12 | Chemie (GDD) | |||
| 4 | T, V, X (E, F, G) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | BA, CA, DA (E, F, G) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 504394.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 7337.0 | |
| All* | Total formula weight | 511731.4 |
