7DFP

Human dopamine D2 receptor in complex with spiperone

Summary for 7DFP

Entry DOI	10.2210/pdb7dfp/pdb
Descriptor	D(2) dopamine receptor,Soluble cytochrome b562, FabL, FabH, ... (4 entities in total)
Functional Keywords	g-protein coupled receptor, dopamine receptor, spiperone, membrane protein, antipsychotic, schizophrenia
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	88313.55
Authors	Im, D.,Shimamura, T.,Iwata, S. (deposition date: 2020-11-09, release date: 2020-12-30, Last modification date: 2023-11-29)
Primary citation	Im, D.,Inoue, A.,Fujiwara, T.,Nakane, T.,Yamanaka, Y.,Uemura, T.,Mori, C.,Shiimura, Y.,Kimura, K.T.,Asada, H.,Nomura, N.,Tanaka, T.,Yamashita, A.,Nango, E.,Tono, K.,Kadji, F.M.N.,Aoki, J.,Iwata, S.,Shimamura, T. Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone. Nat Commun, 11:6442-6442, 2020 Cited by PubMed: 33353947 DOI: 10.1038/s41467-020-20221-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation