7DFP
Human dopamine D2 receptor in complex with spiperone
Summary for 7DFP
Entry DOI | 10.2210/pdb7dfp/pdb |
Descriptor | D(2) dopamine receptor,Soluble cytochrome b562, FabL, FabH, ... (4 entities in total) |
Functional Keywords | g-protein coupled receptor, dopamine receptor, spiperone, membrane protein, antipsychotic, schizophrenia |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 88313.55 |
Authors | Im, D.,Shimamura, T.,Iwata, S. (deposition date: 2020-11-09, release date: 2020-12-30, Last modification date: 2023-11-29) |
Primary citation | Im, D.,Inoue, A.,Fujiwara, T.,Nakane, T.,Yamanaka, Y.,Uemura, T.,Mori, C.,Shiimura, Y.,Kimura, K.T.,Asada, H.,Nomura, N.,Tanaka, T.,Yamashita, A.,Nango, E.,Tono, K.,Kadji, F.M.N.,Aoki, J.,Iwata, S.,Shimamura, T. Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone. Nat Commun, 11:6442-6442, 2020 Cited by PubMed: 33353947DOI: 10.1038/s41467-020-20221-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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