1TB3
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![BU of 1tb3 by Molmil](/molmil-images/mine/1tb3) | Crystal Structure Analysis of Recombinant Rat Kidney Long-chain Hydroxy Acid Oxidase | Descriptor: | ACETIC ACID, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 3 | Authors: | Cunane, L.M, Barton, J.D, Chen, Z.W, Le, K.H.D, Amar, D, Lederer, F, Mathews, F.S. | Deposit date: | 2004-05-19 | Release date: | 2005-02-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure Analysis of Recombinant Rat Kidney Long Chain Hydroxy Acid Oxidase. Biochemistry, 44, 2005
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6BY7
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![BU of 6by7 by Molmil](/molmil-images/mine/6by7) | Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins | Descriptor: | DNA (26-MER), DNA (27-MER), DNA (29-MER), ... | Authors: | Dong, Y, Chen, S, Zhang, S, Sodroski, J, Yang, Z, Liu, D, Mao, Y. | Deposit date: | 2017-12-20 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins. Angew. Chem. Int. Ed. Engl., 57, 2018
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6BQF
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![BU of 6bqf by Molmil](/molmil-images/mine/6bqf) | Pol II elongation complex with 'dT-AP' at i+1, i-1 position | Descriptor: | DNA (5'-D(P*CP*TP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Wang, W, Wang, D. | Deposit date: | 2017-11-27 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1TF9
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![BU of 1tf9 by Molmil](/molmil-images/mine/1tf9) | Streptomyces griseus aminopeptidase complexed with P-Iodo-L-Phenylalanine | Descriptor: | Aminopeptidase, CALCIUM ION, IODO-PHENYLALANINE, ... | Authors: | Reiland, V, Gilboa, R, Spungin-Bialik, A, Schomburg, D, Shoham, Y, Blumberg, S, Shoham, G. | Deposit date: | 2004-05-27 | Release date: | 2005-05-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase. Acta Crystallogr.,Sect.D, 60, 2004
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6C1K
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![BU of 6c1k by Molmil](/molmil-images/mine/6c1k) | HypoPP mutant with ligand1 | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GUANIDINE, Ion transport protein, ... | Authors: | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | Deposit date: | 2018-01-04 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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7U32
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![BU of 7u32 by Molmil](/molmil-images/mine/7u32) | MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution | Descriptor: | CALCIUM ION, DNA EV272, DNA EV273, ... | Authors: | Shan, Z, Pye, V.E, Cherepanov, P, Lyumkis, D. | Deposit date: | 2022-02-25 | Release date: | 2022-05-11 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Multivalent interactions essential for lentiviral integrase function. Nat Commun, 13, 2022
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6C24
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![BU of 6c24 by Molmil](/molmil-images/mine/6c24) | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | Authors: | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | Deposit date: | 2018-01-06 | Release date: | 2018-01-24 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
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6BVB
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![BU of 6bvb by Molmil](/molmil-images/mine/6bvb) | Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C | Descriptor: | Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... | Authors: | Tarade, D, Ohh, M, Lee, J.E. | Deposit date: | 2017-12-12 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9, 2018
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7TOP
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![BU of 7top by Molmil](/molmil-images/mine/7top) | Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20 | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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6BW1
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![BU of 6bw1 by Molmil](/molmil-images/mine/6bw1) | Hendra virus W protein C-terminus in complex with Importin alpha 1 | Descriptor: | Importin subunit alpha-1, Protein W | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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7TOS
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![BU of 7tos by Molmil](/molmil-images/mine/7tos) | E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20 | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7U9I
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![BU of 7u9i by Molmil](/molmil-images/mine/7u9i) | Co-crystal structure of human CARM1 in complex with MT556 inhibitor | Descriptor: | 7-[5-S-(4-{[(4-ethylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Histone-arginine methyltransferase CARM1, UNKNOWN ATOM OR ION | Authors: | Zeng, H, Perveen, S, Dong, A, Hutchinson, A, Seitova, A, Gibson, E, Hajian, T, Li, Y, Gao, Y.D, Schneider, S, Siliphaivanh, P, Sloman, D, Nicholson, B, Fischer, C, Hicks, J, Vedadi, M, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | Deposit date: | 2022-03-10 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Co-crystal structure of human CARM1 in complex with MT556 inhibitor To Be Published
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7WU7
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![BU of 7wu7 by Molmil](/molmil-images/mine/7wu7) | Prefoldin-tubulin-TRiC complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... | Authors: | Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. | Deposit date: | 2022-02-07 | Release date: | 2022-12-21 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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6BGI
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![BU of 6bgi by Molmil](/molmil-images/mine/6bgi) | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | Deposit date: | 2017-10-28 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature, 552, 2017
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1TGZ
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![BU of 1tgz by Molmil](/molmil-images/mine/1tgz) | Structure of human Senp2 in complex with SUMO-1 | Descriptor: | SULFATE ION, Sentrin-specific protease 2, Ubiquitin-like protein SMT3C | Authors: | Reverter, D, Lima, C.D. | Deposit date: | 2004-05-31 | Release date: | 2004-09-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A basis for SUMO protease specificity provided by analysis of human Senp2 and a
Senp2-SUMO complex Structure, 12, 2004
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1TH7
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![BU of 1th7 by Molmil](/molmil-images/mine/1th7) | |
7XA7
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![BU of 7xa7 by Molmil](/molmil-images/mine/7xa7) | Crystal structure of SARS-CoV-2 receptor-binding domain in complex with intermediate horseshoe bat ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | Authors: | Tang, L.F, Zhang, D, Han, P, Qi, J.X. | Deposit date: | 2022-03-17 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2. Int J Biol Sci, 18, 2022
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1UXB
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![BU of 1uxb by Molmil](/molmil-images/mine/1uxb) | ADENOVIRUS AD19p FIBRE HEAD in complex with sialyl-lactose | Descriptor: | ACETATE ION, FIBER PROTEIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | Authors: | Burmeister, W.P, Guilligay, D, Cusack, S, Wadell, G, Arnberg, N. | Deposit date: | 2004-02-24 | Release date: | 2004-07-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites J.Virol., 78, 2004
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7TPK
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![BU of 7tpk by Molmil](/molmil-images/mine/7tpk) | |
6BL5
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![BU of 6bl5 by Molmil](/molmil-images/mine/6bl5) | Head decoration protein from the hyperthermophilic phage P74-26 | Descriptor: | Head decoration protein | Authors: | Stone, N.P, Hilbert, B.J, Hidalgo, D, Halloran, K.T, Kelch, B.A. | Deposit date: | 2017-11-09 | Release date: | 2018-02-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein. Structure, 26, 2018
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7U08
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7TZ6
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![BU of 7tz6 by Molmil](/molmil-images/mine/7tz6) | Structure of mitochondrial bc1 in complex with ck-2-68 | Descriptor: | 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ... | Authors: | Xia, D, Esser, L, Zhou, F, Huang, R. | Deposit date: | 2022-02-15 | Release date: | 2023-02-22 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes. J.Biol.Chem., 299, 2023
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6C2R
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![BU of 6c2r by Molmil](/molmil-images/mine/6c2r) | Aurora A ligand complex | Descriptor: | (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid, Aurora kinase A, SULFATE ION | Authors: | Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S. | Deposit date: | 2018-01-08 | Release date: | 2019-01-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene. Cancer Discov, 9, 2019
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7EKT
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![BU of 7ekt by Molmil](/molmil-images/mine/7ekt) | human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 and PNU-120596 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... | Authors: | Liu, S, Zhao, Y, Sun, D, Tian, C. | Deposit date: | 2021-04-06 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation. Cell Res., 31, 2021
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7U01
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![BU of 7u01 by Molmil](/molmil-images/mine/7u01) | |