7TZ6

Structure of mitochondrial bc1 in complex with ck-2-68

Summary for 7TZ6

Entry DOI	10.2210/pdb7tz6/pdb
EMDB information	26203
Descriptor	Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, Cytochrome b-c1 complex subunit 10, ... (15 entities in total)
Functional Keywords	mitochondrial cytochrome bc1, antimalarial inhibitor, electron transfer, oxidoreductase
Biological source	Bos taurus (cattle) More
Total number of polymer chains	22
Total formula weight	487471.01
Authors	Xia, D.,Esser, L.,Zhou, F.,Huang, R. (deposition date: 2022-02-15, release date: 2023-02-22, Last modification date: 2023-09-06)
Primary citation	Esser, L.,Zhou, F.,Zeher, A.,Wu, W.,Huang, R.,Yu, C.A.,Lane, K.D.,Wellems, T.E.,Xia, D. Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes. J.Biol.Chem., 299:104860-104860, 2023 Cited by PubMed: 37236355 DOI: 10.1016/j.jbc.2023.104860 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.88 Å)

Structure validation