Pol II elongation complex with 'dT-AP' at i+1, i-1 position

Summary for 6BQF

DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (14 entities in total)
Functional Keywordscomplex, dna binding protein, dna-rna hybrid, transcription, transferase-transcription complex, transferase/transcription
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains12
Total molecular weight481863.02
Wang, W.,Wang, D. (deposition date: 2017-11-27, release date: 2018-02-28, Last modification date: 2020-01-01)
Primary citation
Wang, W.,Walmacq, C.,Chong, J.,Kashlev, M.,Wang, D.
Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115:E2538-E2545, 2018
PubMed: 29487211 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1722050115
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2467 0.9% 3.4% 3.2% 0.67MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28