6BQF

Pol II elongation complex with 'dT-AP' at i+1, i-1 position

Summary for 6BQF

DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (14 entities in total)
Functional Keywordscomplex, dna binding protein, dna-rna hybrid, transcription, transferase-transcription complex, transferase/transcription
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Cellular locationNucleus P04050 P08518 P16370 P20434 P20436 P38902
Cytoplasm  P20435
Nucleus, nucleolus  P27999 P22139 P40422
Total number of polymer chains12
Total molecular weight481863.02
Authors
Wang, W.,Wang, D. (deposition date: 2017-11-27, release date: 2018-02-28, Last modification date: 2018-03-21)
Primary citation
Wang, W.,Walmacq, C.,Chong, J.,Kashlev, M.,Wang, D.
Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115:E2538-E2545, 2018
PubMed: 29487211 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1722050115
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.24670.9%3.4%3.2%0.67MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution