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7TOS

E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20

This is a non-PDB format compatible entry.
Summary for 7TOS
Entry DOI10.2210/pdb7tos/pdb
EMDB information26037
Descriptor50S ribosomal protein L2, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (56 entities in total)
Functional Keywordsribosomal binding peptide, als/ftd-associated dipeptide repeat protein, ribosome
Biological sourceEscherichia coli
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Total number of polymer chains56
Total formula weight2170366.17
Authors
Loveland, A.B.,Svidritskiy, E.,Susorov, D.,Lee, S.,Park, A.,Zvornicanin, S.,Demo, G.,Gao, F.B.,Korostelev, A.A. (deposition date: 2022-01-24, release date: 2022-05-25, Last modification date: 2024-02-21)
Primary citationLoveland, A.B.,Svidritskiy, E.,Susorov, D.,Lee, S.,Park, A.,Zvornicanin, S.,Demo, G.,Gao, F.B.,Korostelev, A.A.
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13:2776-2776, 2022
Cited by
PubMed: 35589706
DOI: 10.1038/s41467-022-30418-0
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.9 Å)
Structure validation

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