7TOS
E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L02) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli | Large ribosomal subunit protein uL2 |
| 2 | B (L03) | 50S ribosomal protein L3 | polymer | 209 | 22277.5 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli | Large ribosomal subunit protein uL3 |
| 3 | C (L04) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (L3C159) Pfam (PF00573) UniProt (by SIFTS) (P60723) | Escherichia coli | |
| 4 | D (L05) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 1 | UniProt (A0A4P8BX24) Pfam (PF00281) Pfam (PF00673) UniProt (by SIFTS) (P62399) | Escherichia coli | |
| 5 | E (L06) | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 1 | UniProt (A0A8E0IYC4) Pfam (PF00347) UniProt (by SIFTS) (P0AG55) | Escherichia coli | |
| 6 | F (L09) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (V0YZK9) Pfam (PF03948) Pfam (PF01281) UniProt (by SIFTS) (P0A7R1) | Escherichia coli | |
| 7 | G (L10) | 50S ribosomal protein L10 | polymer | 131 | 14112.3 | 1 | UniProt (A0A6C9HPD7) Pfam (PF00466) UniProt (by SIFTS) (P0A7J3) | Escherichia coli | |
| 8 | H (L11) | 50S ribosomal protein L11 | polymer | 141 | 14763.2 | 1 | UniProt (A0A1X3L9Y5) Pfam (PF03946) Pfam (PF00298) UniProt (by SIFTS) (P0A7J7) | Escherichia coli | |
| 9 | I (L13) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (S1EW51) Pfam (PF00572) UniProt (by SIFTS) (P0AA10) | Escherichia coli | |
| 10 | J (L14) | 50S ribosomal protein L14 | polymer | 122 | 13451.9 | 1 | UniProt (S1NW45) Pfam (PF00238) UniProt (by SIFTS) (P0ADY3) | Escherichia coli | |
| 11 | K (L15) | 50S ribosomal protein L15 | polymer | 143 | 14877.3 | 1 | UniProt (A0A037Y8L6) Pfam (PF00828) UniProt (by SIFTS) (P02413) | Escherichia coli | |
| 12 | L (L16) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli | Large ribosomal subunit protein uL16 |
| 13 | M (L17) | 50S ribosomal protein L17 | polymer | 120 | 13721.9 | 1 | UniProt (A0A829CNM8) Pfam (PF01196) UniProt (by SIFTS) (P0AG44) | Escherichia coli | |
| 14 | N (L18) | 50S ribosomal protein L18 | polymer | 116 | 12663.5 | 1 | UniProt (A0A7U9ARF9) Pfam (PF00861) UniProt (by SIFTS) (P0C018) | Escherichia coli | |
| 15 | O (L19) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 1 | UniProt (A0A7U9BC41) Pfam (PF01245) UniProt (by SIFTS) (P0A7K6) | Escherichia coli | |
| 16 | P (L20) | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 1 | UniProt (L3CCT0) Pfam (PF00453) UniProt (by SIFTS) (P0A7L3) | Escherichia coli | |
| 17 | Q (L21) | Ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (A0A829CSJ4) Pfam (PF00829) UniProt (by SIFTS) (P0AG48) | Escherichia coli | |
| 18 | R (L22) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli | Large ribosomal subunit protein uL22 |
| 19 | S (L23) | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 1 | UniProt (V0YNZ1) Pfam (PF00276) UniProt (by SIFTS) (P0ADZ0) | Escherichia coli | |
| 20 | T (L24) | Ribosomal protein L24 | polymer | 102 | 11078.9 | 1 | UniProt (A0A8E0FZY0) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (P60624) | Escherichia coli | |
| 21 | U (L25) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (D7XH79) Pfam (PF01386) UniProt (by SIFTS) (P68919) | Escherichia coli | |
| 22 | V (L27) | 50S ribosomal protein L27 | polymer | 75 | 8174.4 | 1 | UniProt (A0A7U9BA03) Pfam (PF01016) UniProt (by SIFTS) (P0A7L8) | Escherichia coli | |
| 23 | W (L28) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 1 | UniProt (A0A1X3JA73) Pfam (PF00830) UniProt (by SIFTS) (P0A7M2) | Escherichia coli | |
| 24 | X (L29) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (D6IEL0) Pfam (PF00831) UniProt (by SIFTS) (P0A7M6) | Escherichia coli | |
| 25 | Y (L30) | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 1 | UniProt (A0A829DYV7) Pfam (PF00327) UniProt (by SIFTS) (P0AG51) | Escherichia coli | |
| 26 | Z (L31) | 50S ribosomal protein L31 | polymer | 66 | 7516.7 | 1 | UniProt (V0YYV3) Pfam (PF01197) UniProt (by SIFTS) (P0A7M9) | Escherichia coli | |
| 27 | AA (L32) | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 1 | UniProt (S1FCH9) Pfam (PF01783) UniProt (by SIFTS) (P0A7N4) | Escherichia coli | |
| 28 | BA (L33) | 50S ribosomal protein L33 | polymer | 50 | 5814.8 | 1 | UniProt (L3BZQ9) Pfam (PF00471) UniProt (by SIFTS) (P0A7N9) | Escherichia coli | |
| 29 | CA (L34) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (B7MGC4) Pfam (PF00468) UniProt (by SIFTS) (P0A7P5) | Escherichia coli | |
| 30 | DA (L35) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 1 | UniProt (A0A0E1M2J4) Pfam (PF01632) UniProt (by SIFTS) (P0A7Q1) | Escherichia coli | |
| 31 | EA (L36) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (A0A0E2L017) Pfam (PF00444) UniProt (by SIFTS) (P0A7Q6) | Escherichia coli | |
| 32 | FA (S02) | 30S ribosomal protein S2 | polymer | 225 | 25015.8 | 1 | UniProt (C3TPN2) Pfam (PF00318) UniProt (by SIFTS) (P0A7V0) | Escherichia coli | |
| 33 | GA (S03) | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 1 | UniProt (A0A376HTV6) Pfam (PF07650) Pfam (PF00189) UniProt (by SIFTS) (P0A7V3) | Escherichia coli | |
| 34 | HA (S04) | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 1 | UniProt (L3PZ69) Pfam (PF00163) Pfam (PF01479) UniProt (by SIFTS) (P0A7V8) | Escherichia coli | |
| 35 | IA (S05) | 30S ribosomal protein S5 | polymer | 157 | 16532.1 | 1 | UniProt (F4TL26) Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (P0A7W1) | Escherichia coli | |
| 36 | JA (S06) | 30S ribosomal protein S6, non-modified isoform | polymer | 100 | 11669.4 | 1 | UniProt (P02358) Pfam (PF01250) | Escherichia coli | |
| 37 | KA (S07) | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 1 | UniProt (P02359) Pfam (PF00177) | Escherichia coli | Small ribosomal subunit protein uS7 |
| 38 | LA (S08) | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 1 | UniProt (D8A1L7) Pfam (PF00410) UniProt (by SIFTS) (P0A7W7) | Escherichia coli | |
| 39 | MA (S09) | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 1 | UniProt (A0A1X3KYI7) Pfam (PF00380) UniProt (by SIFTS) (P0A7X3) | Escherichia coli | |
| 40 | NA (S10) | 30S ribosomal protein S10 | polymer | 98 | 11197.0 | 1 | UniProt (A0A5B9AU26) Pfam (PF00338) UniProt (by SIFTS) (P0A7R5) | Escherichia coli | |
| 41 | OA (S11) | 30S ribosomal protein S11 | polymer | 116 | 12388.1 | 1 | UniProt (I2UH22) Pfam (PF00411) UniProt (by SIFTS) (P0A7R9) | Escherichia coli | |
| 42 | PA (S12) | 30S ribosomal protein S12 | polymer | 123 | 13637.0 | 1 | UniProt (I2UHF1) Pfam (PF00164) UniProt (by SIFTS) (P0A7S3) | Escherichia coli | |
| 43 | QA (S13) | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 1 | UniProt (A0A1X3KX08) Pfam (PF00416) UniProt (by SIFTS) (P0A7S9) | Escherichia coli | |
| 44 | RA (S14) | 30S ribosomal protein S14 | polymer | 100 | 11475.4 | 1 | UniProt (A0A829E173) Pfam (PF00253) UniProt (by SIFTS) (P0AG59) | Escherichia coli | |
| 45 | SA (S15) | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 1 | UniProt (D7XN21) Pfam (PF00312) UniProt (by SIFTS) (P0ADZ4) | Escherichia coli | |
| 46 | TA (S16) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (B7MIU7) Pfam (PF00886) UniProt (by SIFTS) (P0A7T3) | Escherichia coli | |
| 47 | UA (S17) | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 1 | UniProt (A0A080IK26) Pfam (PF00366) UniProt (by SIFTS) (P0AG63) | Escherichia coli | |
| 48 | VA (S18) | 30S ribosomal protein S18 | polymer | 65 | 7606.8 | 1 | UniProt (E0J6I2) Pfam (PF01084) UniProt (by SIFTS) (P0A7T7) | Escherichia coli | |
| 49 | WA (S19) | 30S ribosomal protein S19 | polymer | 79 | 9057.6 | 1 | UniProt (S1EA57) Pfam (PF00203) UniProt (by SIFTS) (P0A7U3) | Escherichia coli | |
| 50 | XA (S20) | 30S ribosomal protein S20 | polymer | 85 | 9506.2 | 1 | UniProt (C3TRH7) Pfam (PF01649) UniProt (by SIFTS) (P0A7U7) | Escherichia coli | |
| 51 | YA (S21) | Ribosomal protein S21 | polymer | 65 | 7763.1 | 1 | UniProt (A0A8E0HV98) Pfam (PF01165) UniProt (by SIFTS) (P68679) | Escherichia coli | |
| 52 | ZA (L1) | 50S ribosomal protein L1 | polymer | 223 | 23735.5 | 1 | UniProt (A0A4Y8DMK0) Pfam (PF00687) UniProt (by SIFTS) (P0A7L0) | Escherichia coli | |
| 53 | AB (16S) | 16S ribosomal RNA | polymer | 1539 | 498725.4 | 1 | GenBank (1338015391) | Escherichia coli | |
| 54 | BB (23S) | 23S ribosomal RNA | polymer | 2903 | 941305.3 | 1 | GenBank (1036415628) | Escherichia coli | |
| 55 | CB (5S) | 5S ribosomal RNA | polymer | 120 | 38813.1 | 1 | GenBank (1370526515) | Escherichia coli | |
| 56 | DB (PR) | PR20, ALS/FTD dipeptide repeat protein | polymer | 40 | 5104.2 | 1 | Homo sapiens |
Sequence modifications
23S: 1 - 2903 (GenBank: 1036415628)
5S: 1 - 119 (GenBank: 1370526515)
| PDB | External Database | Details |
|---|---|---|
| C 747 | U 1155325 | variant |
| PDB | External Database | Details |
|---|---|---|
| A 120 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 56 |
| Total formula weight | 2170366.2 | |
| All* | Total formula weight | 2170366.2 |
