8GRB
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8GRU
| Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | Descriptor: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-02 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRH
| Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT | Descriptor: | CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.506 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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5W2M
| APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION | Authors: | Fang, Y, Xiao, X, Li, S.-X, Wolfe, A, Chen, X.S. | Deposit date: | 2017-06-06 | Release date: | 2017-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA. J. Mol. Biol., 430, 2018
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6CU1
| X-ray structure of the S. typhimurium YrlA effector-binding module | Descriptor: | MAGNESIUM ION, SULFATE ION, YrlA effector-binding module | Authors: | Wang, W, Chen, X, Wolin, S.L, Xiong, Y. | Deposit date: | 2018-03-23 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for tRNA Mimicry by a Bacterial Y RNA. Structure, 26, 2018
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8HHG
| The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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8HHH
| The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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5ESW
| Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila | Descriptor: | PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
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5ESX
| Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
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1QET
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | Descriptor: | RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3') | Authors: | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | Deposit date: | 1997-03-04 | Release date: | 1997-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
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5W45
| Crystal structure of APOBEC3H | Descriptor: | APOBEC3H, ZINC ION | Authors: | Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S. | Deposit date: | 2017-06-09 | Release date: | 2018-03-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.486 Å) | Cite: | Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H. Sci Rep, 8, 2018
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7YDI
| SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | Deposit date: | 2022-07-04 | Release date: | 2022-08-24 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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1QES
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | Descriptor: | RNA (5'-R(*GP*GP*AP*GP*UP*UP*CP*C)-3') | Authors: | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | Deposit date: | 1997-03-04 | Release date: | 1997-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
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4GDF
| A Crystal Structure of SV40 Large T Antigen | Descriptor: | DNA (32-MER), Large T antigen, ZINC ION | Authors: | Chang, Y.P, Xu, M, Chen, X.S. | Deposit date: | 2012-07-31 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen. Cell Rep, 3, 2013
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3VCB
| C425S mutant of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | Descriptor: | RNA-directed RNA polymerase | Authors: | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | Deposit date: | 2012-01-03 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. Plos One, 4, 2009
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8JZU
| SLC15A4_TASL complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein | Authors: | Zhang, S.S, Chen, X.D, Xie, M. | Deposit date: | 2023-07-06 | Release date: | 2023-09-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
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8JZS
| Outward-facing SLC15A4 dimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter | Authors: | Zhang, S.S, Chen, X.D, Xie, M. | Deposit date: | 2023-07-06 | Release date: | 2023-09-27 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
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8JZR
| Outward_facing SLC15A4 monomer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag | Authors: | Zhang, S.S, Chen, X.D, Xie, M. | Deposit date: | 2023-07-06 | Release date: | 2023-09-27 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
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3VC8
| Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | Descriptor: | RNA-directed RNA polymerase | Authors: | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | Deposit date: | 2012-01-03 | Release date: | 2012-01-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. Plos One, 4, 2009
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3HFH
| Crystal structure of tandem FF domains | Descriptor: | Transcription elongation regulator 1 | Authors: | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | Deposit date: | 2009-05-11 | Release date: | 2009-08-18 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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6CKM
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6CKJ
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6CKL
| N. meningitidis CMP-sialic acid synthetase in the presence of CMP and Neu5Ac2en | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CHLORIDE ION, CITRATE ANION, ... | Authors: | Matthews, M.M, Fisher, A.J, Chen, X. | Deposit date: | 2018-02-28 | Release date: | 2019-03-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.684 Å) | Cite: | Catalytic Cycle ofNeisseria meningitidisCMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Biochemistry, 2019
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3G5C
| Structural and biochemical studies on the ectodomain of human ADAM22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION | Authors: | Liu, H, Shim, A, Chen, X, He, X. | Deposit date: | 2009-02-04 | Release date: | 2009-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural and biochemical studies on the ectodomain of human ADAM22 J.Biol.Chem., 2009
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2E0H
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