6CKL

N. meningitidis CMP-sialic acid synthetase in the presence of CMP and Neu5Ac2en

Summary for 6CKL

Entry DOI	10.2210/pdb6ckl/pdb
Descriptor	N-acylneuraminate cytidylyltransferase, CYTIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	polysaccharide synthesis, sialic acid-activator, cmp-transferase, transferase
Biological source	Neisseria meningitidis
Total number of polymer chains	3
Total formula weight	77089.14
Authors	Matthews, M.M.,Fisher, A.J.,Chen, X. (deposition date: 2018-02-28, release date: 2019-03-06, Last modification date: 2023-10-04)
Primary citation	Matthews, M.M.,McArthur, J.B.,Li, Y.,Yu, H.,Chen, X.,Fisher, A.J. Catalytic Cycle ofNeisseria meningitidisCMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Biochemistry, 2019 Cited by PubMed: 31583886 DOI: 10.1021/acs.biochem.9b00517 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.684 Å)

Structure validation