8JZU

SLC15A4_TASL complex

Summary for 8JZU

Entry DOI	10.2210/pdb8jzu/pdb
EMDB information	36753
Descriptor	lysosomal transporter, TLR adapter interacting with SLC15A4 on the lysosome, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	endolysosomal transporter, protein transport
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	96232.18
Authors	Zhang, S.S.,Chen, X.D.,Xie, M. (deposition date: 2023-07-06, release date: 2023-09-27, Last modification date: 2023-11-01)
Primary citation	Chen, X.,Xie, M.,Zhang, S.,Monguio-Tortajada, M.,Yin, J.,Liu, C.,Zhang, Y.,Delacretaz, M.,Song, M.,Wang, Y.,Dong, L.,Ding, Q.,Zhou, B.,Tian, X.,Deng, H.,Xu, L.,Liu, X.,Yang, Z.,Chang, Q.,Na, J.,Zeng, W.,Superti-Furga, G.,Rebsamen, M.,Yang, M. Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14:6627-6627, 2023 Cited by PubMed: 37863913 DOI: 10.1038/s41467-023-42210-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.05 Å)

Structure validation