8WZX
| Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7 | Descriptor: | Major prion protein | Authors: | Lee, C.-H, Saw, J.-E, Chen, E, Wang, C.-H, Chen, R. | Deposit date: | 2023-11-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils. J.Mol.Biol., 436, 2024
|
|
5O4P
| Crystal structure of AMPylated GRP78 | Descriptor: | 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, SULFATE ION | Authors: | Yan, Y, Chen, R, Ron, D, Read, R. | Deposit date: | 2017-05-30 | Release date: | 2017-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
|
|
5ZXF
| The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a | Descriptor: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | Authors: | Cheng, X.Y, Su, Z.D, Pi, N, Cao, C.Z, Zhao, Z.T, Zhou, J.J, Chen, R, Kuang, Z.K, Huang, Y.Q. | Deposit date: | 2018-05-19 | Release date: | 2018-08-22 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a To Be Published
|
|
8ZJV
| Crystal Structure of the ERK2 complexed with 5-Iodotubercidin | Descriptor: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Yang, Y, Fu, L, Chen, R, Cheng, H, Sun, X. | Deposit date: | 2024-05-15 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the ERK2 complexed with 5-Iodotubercidin To Be Published
|
|
6A6X
| The crystal structure of the Mtb MazE-MazF-mt9 complex | Descriptor: | Antitoxin MazE7, Probable endoribonuclease MazF7, SULFATE ION | Authors: | Xie, W, Chen, R, Tu, J. | Deposit date: | 2018-06-29 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Biochemical Characterization of the Cognate and Heterologous Interactions of the MazEF-mt9 TA System. Acs Infect Dis., 5, 2019
|
|
6JFP
| Crystal structure of the beta-glucosidase Bgl15 | Descriptor: | beta-D-glucopyranose, beta-glucosidase 15 | Authors: | Xie, W, Chen, R. | Deposit date: | 2019-02-11 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Engineering of beta-Glucosidase Bgl15 with Simultaneously Enhanced Glucose Tolerance and Thermostability To Improve Its Performance in High-Solid Cellulose Hydrolysis. J.Agric.Food Chem., 68, 2020
|
|
8HCU
| Crystal structure of BCOR/PCGF1/KDM2B complex | Descriptor: | ACETIC ACID, BCL-6 corepressor, Polycomb group RING finger protein 1, ... | Authors: | Shen, F, Chen, R, Xu, J, Liu, J. | Deposit date: | 2022-11-03 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of BCOR/PCGF1/KDM2B complex to be published
|
|
8ZMN
| Crystal structure of ANTXR1 | Descriptor: | Anthrax toxin receptor 1, SODIUM ION | Authors: | Zheng, H, Hu, J, Fu, L, Chen, R. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | X-ray structure of Anthrax toxin receptor 1 APO from Rattus norvegicus To Be Published
|
|
3R3G
| Structure of human thrombin with residues 145-150 of murine thrombin. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Thrombin Heavy Chain, ... | Authors: | Pozzi, N, Chen, R, Chen, Z, Bah, A, Di Cera, E. | Deposit date: | 2011-03-15 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Rigidification of the autolysis loop enhances Na(+) binding to thrombin. Biophys.Chem., 159, 2011
|
|
3QQ3
| Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides | Descriptor: | 9-mer peptide from Neuraminidase, Beta-2-microglobulin, MHC class I antigen | Authors: | Zhang, N, Qi, J, Gao, F, Pan, X, Chen, R, Li, Q, Chen, Z, Li, X, Xia, C, Gao, G.F. | Deposit date: | 2011-02-15 | Release date: | 2011-12-28 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides. J.Virol., 85, 2011
|
|
3QQ4
| Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides | Descriptor: | Beta-2-microglobulin, MHC class I antigen, VP35 | Authors: | Zhang, N, Qi, J, Gao, F, Pan, X, Chen, R, Li, Q, Chen, Z, Li, X, Xia, C, Gao, G.F. | Deposit date: | 2011-02-15 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides. J.Virol., 85, 2011
|
|
4ZRS
| Crystal structure of a cloned feruloyl esterase from a soil metagenomic library | Descriptor: | Esterase, GLYCEROL | Authors: | Xie, W, Chen, R, Cao, L, Liu, Y. | Deposit date: | 2015-05-12 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enhancing the Thermostability of Feruloyl Esterase EstF27 by Directed Evolution and the Underlying Structural Basis J.Agric.Food Chem., 63, 2015
|
|
4ZUS
| Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide REV-QW11 | Descriptor: | Beta-2-microglobulin, Classical MHC class I antigen, GLN-ALA-GLU-VAL-LEU-GLN-GLU-ARG-LEU-GLU-TRP | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
|
|
4ZUW
| Crystal structure of Equine MHC I(Eqca-N*00601) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-GW12 | Descriptor: | Beta-2-microglobulin, Classical MHC class I antigen, GLY-SER-GLN-LYS-LEU-THR-THR-GLY-ASN-CYS-ASN-TRP | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
|
|
4ZUV
| Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Env-RW12 | Descriptor: | ARG-VAL-GLU-ASP-VAL-THR-ASN-THR-ALA-GLU-TYR-TRP, Beta-2-microglobulin, Classical MHC class I antigen | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
|
|
4ZUU
| Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-CF9 | Descriptor: | Beta-2-microglobulin, CYS-THR-SER-GLU-GLU-MET-ASN-ALA-PHE, Classical MHC class I antigen | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
|
|
4ZUT
| Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-GW12 | Descriptor: | Beta-2-microglobulin, Classical MHC class I antigen, GLY-SER-GLN-LYS-LEU-THR-THR-GLY-ASN-CYS-ASN-TRP | Authors: | Yao, S, Liu, J, Qi, J, Chen, R, Zhang, N, Liu, Y, Xia, C. | Deposit date: | 2015-05-17 | Release date: | 2016-04-06 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles J Immunol., 196, 2016
|
|
2IJ9
| Crystal Structure of Uridylate Kinase from Archaeoglobus Fulgidus | Descriptor: | SULFATE ION, Uridylate kinase | Authors: | Patskovsky, Y, Chen, R, Keefe, L.J, Sauder, J.M, Dickey, M, Adams, J.M, Ozyurt, S, Wasserman, S.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-09-29 | Release date: | 2006-10-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of Uridylate Kinase from Archaeoglobus Fulgidus To be Published
|
|
5Z02
| Crystal structure of HIS6-tagged Mdm2 with nutlin-3a | Descriptor: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | Authors: | Su, Z.D, Cheng, X.Y, Chen, R, Pi, N. | Deposit date: | 2017-12-18 | Release date: | 2018-01-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a to be published
|
|
6O96
| Dot1L bound to the H2BK120 Ubiquitinated nucleosome | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Vasilyev, N, Chen, R, Nudler, E, Armache, J.-P, Armache, K.-J. | Deposit date: | 2019-03-13 | Release date: | 2019-04-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination. Mol.Cell, 74, 2019
|
|
7BV5
| Crystal structure of the yeast heterodimeric ADAT2/3 | Descriptor: | ZINC ION, tRNA-specific adenosine deaminase subunit TAD2, tRNA-specific adenosine deaminase subunit TAD3 | Authors: | Xie, W, Liu, X, Chen, R, Sun, Y, Chen, R, Zhou, J, Tian, Q. | Deposit date: | 2020-04-09 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the yeast heterodimeric ADAT2/3 deaminase. Bmc Biol., 18, 2020
|
|
5WYG
| The crystal structure of the apo form of Mtb MazF | Descriptor: | Probable endoribonuclease MazF7 | Authors: | Xie, W, Chen, R, Tu, J. | Deposit date: | 2017-01-13 | Release date: | 2017-04-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.356 Å) | Cite: | Structure of the MazF-mt9 toxin, a tRNA-specific endonuclease from Mycobacterium tuberculosis Biochem. Biophys. Res. Commun., 486, 2017
|
|
6L29
| The structure of the MazF-mt1 mutant | Descriptor: | mRNA interferase | Authors: | Xie, W, Chen, R, Zhou, J. | Deposit date: | 2019-10-02 | Release date: | 2020-08-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3000052 Å) | Cite: | Conserved Conformational Changes in the Regulation ofMycobacterium tuberculosisMazEF-mt1. Acs Infect Dis., 6, 2020
|
|
6KYT
| The structure of the M. tb toxin MazEF-mt1 complex | Descriptor: | Antitoxin MazE9, Endoribonuclease MazF9 | Authors: | Xie, W, Chen, R, Zhou, J. | Deposit date: | 2019-09-20 | Release date: | 2020-08-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.00101161 Å) | Cite: | Conserved Conformational Changes in the Regulation ofMycobacterium tuberculosisMazEF-mt1. Acs Infect Dis., 6, 2020
|
|
6KYS
| The structure of the M. tb toxin MazF-mt1 | Descriptor: | Endoribonuclease MazF9 | Authors: | Xie, W, Chen, R, Zhou, J. | Deposit date: | 2019-09-20 | Release date: | 2020-08-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.200414 Å) | Cite: | Conserved Conformational Changes in the Regulation ofMycobacterium tuberculosisMazEF-mt1. Acs Infect Dis., 6, 2020
|
|