3R3G

Structure of human thrombin with residues 145-150 of murine thrombin.

Summary for 3R3G

Related1SHH
DescriptorThrombin Light Chain, Thrombin Heavy Chain, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordsserine protease, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space P00734 P00734
Total number of polymer chains2
Total molecular weight33879.64
Authors
Pozzi, N.,Chen, R.,Chen, Z.,Bah, A.,Di Cera, E. (deposition date: 2011-03-15, release date: 2011-05-11, Last modification date: 2011-09-21)
Primary citation
Pozzi, N.,Chen, R.,Chen, Z.,Bah, A.,Di Cera, E.
Rigidification of the autolysis loop enhances Na(+) binding to thrombin.
Biophys.Chem., 159:6-13, 2011
PubMed: 21536369 (PDB entries with the same primary citation)
DOI: 10.1016/j.bpc.2011.04.003
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.224506.0%7.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3r3g
no rotation
Molmil generated image of 3r3g
rotated about x axis by 90°
Molmil generated image of 3r3g
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3r3g
no rotation
Molmil generated image of 3r3g
rotated about x axis by 90°
Molmil generated image of 3r3g
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3r3g.pdb1.gz [107.79 KB])
Coordinate files for Biological unit (3r3g.pdb2.gz [213.42 KB])