3R3G
Structure of human thrombin with residues 145-150 of murine thrombin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thrombin Light Chain | polymer | 31 | 3647.1 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | Coagulation factor II |
| 2 | B | Thrombin Heavy Chain | polymer | 259 | 29965.4 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II |
| 3 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Arg 145 | Lys 508 | engineered mutation |
| Thr 149 | Ala 513 | engineered mutation |
| Ile 149 | Val 515 | engineered mutation |
| Asn 149 | Gly 516 | engineered mutation |
| Glu 149 | Lys 517 | engineered mutation |
| Ile 150 | Gly 518 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33612.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 267.2 | |
| All* | Total formula weight | 33879.6 |
