8WZX
Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7
Summary for 8WZX
Entry DOI | 10.2210/pdb8wzx/pdb |
EMDB information | 37963 |
Descriptor | Major prion protein (1 entity in total) |
Functional Keywords | prion, 23-144, hamster, prp, protein fibril |
Biological source | Mesocricetus auratus (golden hamster) |
Total number of polymer chains | 20 |
Total formula weight | 247532.84 |
Authors | Lee, C.-H.,Saw, J.-E.,Chen, E.,Wang, C.-H.,Chen, R. (deposition date: 2023-11-02, release date: 2024-05-01, Last modification date: 2024-05-08) |
Primary citation | Lee, C.H.,Saw, J.E.,Chen, E.H.,Wang, C.H.,Uchihashi, T.,Chen, R.P. The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils. J.Mol.Biol., 436:168576-168576, 2024 Cited by PubMed: 38641239DOI: 10.1016/j.jmb.2024.168576 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.88 Å) |
Structure validation
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