8WZX

Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7

Summary for 8WZX

Entry DOI	10.2210/pdb8wzx/pdb
EMDB information	37963
Descriptor	Major prion protein (1 entity in total)
Functional Keywords	prion, 23-144, hamster, prp, protein fibril
Biological source	Mesocricetus auratus (golden hamster)
Total number of polymer chains	20
Total formula weight	247532.84
Authors	Lee, C.-H.,Saw, J.-E.,Chen, E.,Wang, C.-H.,Chen, R. (deposition date: 2023-11-02, release date: 2024-05-01, Last modification date: 2024-05-08)
Primary citation	Lee, C.H.,Saw, J.E.,Chen, E.H.,Wang, C.H.,Uchihashi, T.,Chen, R.P. The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils. J.Mol.Biol., 436:168576-168576, 2024 Cited by PubMed: 38641239 DOI: 10.1016/j.jmb.2024.168576 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.88 Å)

Structure validation