PDB Search results for query - 일본 단백질구조 데이터 뱅크

PDB: 380 results

Crystal structure of YTHDC1 in complex with Compound 37 (ZA_356)
Descriptor:	2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-cyclopropyl-7,8-dihydropurin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.36 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 37 (ZA_356) To Be Published

8Q2T

Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236)
Descriptor:	2-chloranyl-~{N}-methyl-9-(phenylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.41 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236) To Be Published

8Q2U

Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308)
Descriptor:	2-chloranyl-~{N}-methyl-9-(pyridin-4-ylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.36 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308) To Be Published

8Q37

Crystal structure of YTHDC1 in complex with Compound 18 (ZA_312)
Descriptor:	2-chloranyl-9-[(2-methoxyphenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.28 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 18 (ZA_312) To Be Published

8Q2V

Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560)
Descriptor:	2-chloranyl-~{N}-methyl-9-[(2~{S})-oxan-2-yl]purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.71 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560) To Be Published

8Q2Y

Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572)
Descriptor:	2-[2-chloranyl-6-(methylamino)purin-9-yl]-~{N}-phenyl-ethanamide, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.71 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572) To Be Published

8Q3G

Crystal structure of YTHDC1 in complex with Compound 23 (ZA_385)
Descriptor:	3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]-~{N}-methyl-benzamide, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-04
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 23 (ZA_385) To Be Published

8Q4M

Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349)
Descriptor:	2-chloranyl-9-[(3-chlorophenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.43 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 25 (ZA_349) To Be Published

8Q4P

Crystal structure of YTHDC1 in complex with Compound 27 (ZA_309)
Descriptor:	2-chloranyl-9-[(3-methoxyphenyl)methyl]-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.43 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 27 (ZA_309) To Be Published

8Q38

Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347)
Descriptor:	SULFATE ION, YTH domain-containing protein 1, methyl 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoate
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347) To Be Published

8Q4T

Crystal structure of YTHDC1 in complex with Compound 31 (ZA_400)
Descriptor:	SULFATE ION, YTH domain-containing protein 1, ~{N}-[4-chloranyl-2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 31 (ZA_400) To Be Published

8Q39

Crystal structure of YTHDC1 in complex with Compound 21 (ZA_515)
Descriptor:	2-chloranyl-N-methyl-9-[[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl]purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 21 (ZA_515) To Be Published

8Q2R

Crystal structure of YTHDC1 in complex with Compound 3 (ZA_431)
Descriptor:	5-chloranyl-~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Li, Y, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 3 (ZA_431) To Be Published

8Q4U

Crystal structure of YTHDC1 in complex with Compound 36 (ZA_540b)
Descriptor:	9-[(3-chlorophenyl)methyl]-2-fluoranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.37 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 36 (ZA_540b) To Be Published

8Q2S

Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232)
Descriptor:	2-chloranyl-~{N}-methyl-9-phenyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.41 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232) To Be Published

8Q31

Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341)
Descriptor:	9-[(2-aminophenyl)methyl]-2-chloranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.32 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341) To Be Published

8Q35

Crystal structure of YTHDC1 in complex with Compound 16 (ZA_354)
Descriptor:	9-[[2-[bis(fluoranyl)methyl]phenyl]methyl]-2-chloranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.31 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 16 (ZA_354) To Be Published

8Q4Q

Crystal structure of YTHDC1 in complex with Compound 29 (ZA_337)
Descriptor:	4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoic acid, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 29 (ZA_337) To Be Published

8Q2Q

Crystal structure of YTHDC1 in complex with Compound 2b (YL_32)
Descriptor:	2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Li, Y, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.3 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 2b (YL_32) To Be Published

8Q32

Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364)
Descriptor:	SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-03
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.43 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364) To Be Published

8Q4N

Crystal structure of YTHDC1 in complex with Compound 26 (ZA_513)
Descriptor:	3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzenecarbonitrile, SULFATE ION, YTH domain-containing protein 1
Authors:	Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:	2023-08-07
Release date:	2023-12-06
Method:	X-RAY DIFFRACTION (1.42 Å)
Cite:	Crystal structure of YTHDC1 in complex with Compound 26 (ZA_513) To Be Published

6ZD5

Crystal structure of YTHDC1 S378A mutant complex with m6A
Descriptor:	N-methyladenosine, SULFATE ION, YTH domain containing 1
Authors:	Bedi, R.K, Li, Y, Caflisch, A.
Deposit date:	2020-06-13
Release date:	2021-01-13
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021

5MME

Crystal structure of CREBBP bromodomain complexd with US46C
Descriptor:	CREB-binding protein, dimethyl 5-[(5-ethanoyl-2-ethoxy-phenyl)amino]benzene-1,3-dicarboxylate
Authors:	Zhu, J, Caflisch, A.
Deposit date:	2016-12-09
Release date:	2017-12-20
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules. ACS Med Chem Lett, 9, 2018

6YKE

Crystal structure of YTHDC1 with compound DHU_DC1_038
Descriptor:	(2~{R})-2-(3-fluorophenyl)-5,5-dimethyl-morpholine, SULFATE ION, YTHDC1
Authors:	Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A.
Deposit date:	2020-04-06
Release date:	2020-07-15
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.52 Å)
Cite:	Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022

6YNN

Crystal structure of YTHDC1 with compound DHU_DC1_135
Descriptor:	6-[[(2-chloranyl-6-fluoranyl-phenyl)methyl-methyl-amino]methyl]-1~{H}-pyrimidine-2,4-dione, SULFATE ION, YTHDC1
Authors:	Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A.
Deposit date:	2020-04-14
Release date:	2020-07-15
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.2 Å)
Cite:	Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021

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Total results:	380
Displayed results:	25
Sorted by:	Hit score (from highest)
Deposition authors:	"Caflisch, A"