7BLA

BAZ2A bromodomain in complex with TP-238 chemical probe

Summary for 7BLA

• Entry DOI: 10.2210/pdb7bla/pdb
• Related: 7BL8 7BL9 7KDZ
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 12822.45

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2021-01-18, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Chemical probes in the BAZ2A bromodomain; to be published,

Experimental method

X-RAY DIFFRACTION (1.086 Å)