7PL1

Crystal structure of human METTL1 bound to Sinefungin

Summary for 7PL1

Entry DOI	10.2210/pdb7pl1/pdb
Descriptor	tRNA (guanine-N(7)-)-methyltransferase, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	methyltranferase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	30154.36
Authors	Nai, F.,Caflisch, A. (deposition date: 2021-08-27, release date: 2021-09-15, Last modification date: 2023-12-20)
Primary citation	Nai, F.,Flores Espinoza, M.P.,Invernizzi, A.,Vargas-Rosales, P.A.,Bobileva, O.,Herok, M.,Caflisch, A. Small-Molecule Inhibitors of the m7G-RNA Writer METTL1 Acs Bio Med Chem Au, 2023 Cited by DOI: 10.1021/acsbiomedchemau.3c00030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation