5V7O
 
 | | Crystal Structure of NosK from Streptomyces actuosus | | 分子名称: | NosK, SULFATE ION | | 著者 | Booker, S.J, Boal, A.K, Grove, T.L, Badding, E.D. | | 登録日 | 2017-03-20 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.
J. Am. Chem. Soc., 139, 2017
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7TOM
 | | X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with bacterial lipid substrate analog, 5'deoxyadenosine, and methionine bound | | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5'-DEOXYADENOSINE, FE (III) ION, ... | | 著者 | Lloyd, C.T, Booker, S.J, Boal, A.K. | | 登録日 | 2022-01-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Discovery, structure and mechanism of a tetraether lipid synthase.
Nature, 609, 2022
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7TOL
 | | X-ray crystal structure of glycerol dibiphytanyl glycerol tetraether - macrocyclic archaeol synthase (GDGT-MAS) from Methanocaldococcus jannaschii with archaeal lipid, 5'deoxyadenosine, and methionine bound | | 分子名称: | 3-PHOSPHORYL-[1,2-DI-PHYTANYL]GLYCEROL, 3-[GLYCEROLYLPHOSPHONYL]-[1,2-DI-PHYTANYL]GLYCEROL, 5'-DEOXYADENOSINE, ... | | 著者 | Lloyd, C.T, Booker, S.J, Boal, A.K. | | 登録日 | 2022-01-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Discovery, structure and mechanism of a tetraether lipid synthase.
Nature, 609, 2022
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4ZK6
 | | Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States | | 分子名称: | ACETATE ION, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | | 著者 | Esakova, O.A, Grove, T.L, Saunders, A.H, Yennawar, N.H, Booker, S.J. | | 登録日 | 2015-04-29 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid.
J.Am.Chem.Soc., 138, 2016
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6WTE
 | | Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with cobalamin and [4Fe-4S] cluster bound | | 分子名称: | 1,2-ETHANEDIOL, B12-binding domain-containing protein, COBALAMIN, ... | | 著者 | Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J. | | 登録日 | 2020-05-02 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
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6WTF
 | | Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound | | 分子名称: | COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ... | | 著者 | Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J. | | 登録日 | 2020-05-02 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
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3EPM
 | | Crystal structure of Caulobacter crescentus ThiC | | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ... | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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3EPN
 | | Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide | | 分子名称: | 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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3EPO
 | | Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P | | 分子名称: | (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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7MJV
 | | MiaB in the complex with s-adenosylmethionine and RNA | | 分子名称: | FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Nature, 597, 2021
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7MJZ
 | | The structure of MiaB with pentasulfide bridge | | 分子名称: | IRON/SULFUR CLUSTER, PENTASULFIDE-SULFUR, SODIUM ION, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Nature, 597, 2021
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7MJW
 | | Methylated MiaB in the complex with 5'-deoxyadenosine, methionine and RNA | | 分子名称: | 5'-DEOXYADENOSINE, FE3-S4 methylated cluster, IRON/SULFUR CLUSTER, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Nature, 597, 2021
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7MJY
 | | MiaB in the complex with s-adenosyl-L-homocysteine and RNA | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE3-S4 CLUSTER, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Nature, 597, 2021
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7MJX
 | | MiaB in the complex with 5'-deoxyadenosine, methionine and RNA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-DEOXYADENOSINE, FE3-S4 CLUSTER, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Arcinas, A.J, Wang, B, Krebs, C, Almo, S.C, Booker, S.J. | | 登録日 | 2021-04-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Nature, 597, 2021
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6NSO
 | | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, IRON/SULFUR CLUSTER, Quinolinate synthase A | | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | | 登録日 | 2019-01-25 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141, 2019
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6NSU
 | | Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States | | 分子名称: | DIDEHYDROASPARTATE, IRON/SULFUR CLUSTER, Quinolinate synthase A | | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | | 登録日 | 2019-01-25 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141, 2019
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6OR8
 | | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | | 分子名称: | 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, IRON/SULFUR CLUSTER, PHOSPHATE ION, ... | | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Booker, S.J. | | 登録日 | 2019-04-29 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141, 2019
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6ORA
 | | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | | 分子名称: | (2~{Z})-2-(1-oxidanyl-3-oxidanylidene-propyl)iminobutanedioic acid, 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, ACETATE ION, ... | | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | | 登録日 | 2019-04-29 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141, 2019
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7KDY
 | | Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, methionine, and (2R)-pantetheinylated carbapenam | | 分子名称: | (2R,3R,5R)-3-{[2-({N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... | | 著者 | Knox, H.L, Booker, S.J, Boal, A.K. | | 登録日 | 2020-10-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | | 主引用文献 | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis.
Nature, 602, 2022
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7KDX
 | | Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, and methionine | | 分子名称: | 1,2-ETHANEDIOL, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | | 著者 | Knox, H.L, Booker, S.J, Boal, A.K. | | 登録日 | 2020-10-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis.
Nature, 602, 2022
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3RFA
 | | X-ray structure of RlmN from Escherichia coli in complex with S-adenosylmethionine | | 分子名称: | IRON/SULFUR CLUSTER, Ribosomal RNA large subunit methyltransferase N, S-ADENOSYLMETHIONINE | | 著者 | Boal, A.K, Grove, T.L, McLaughlin, M.I, Yennawar, N, Booker, S.J, Rosenzweig, A.C. | | 登録日 | 2011-04-05 | | 公開日 | 2011-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
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3RF9
 | | X-ray structure of RlmN from Escherichia coli | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, IRON/SULFUR CLUSTER, Ribosomal RNA large subunit methyltransferase N | | 著者 | Boal, A.K, Grove, T.L, McLaughlin, M.I, Yennawar, N, Booker, S.J, Rosenzweig, A.C. | | 登録日 | 2011-04-05 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
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5EXJ
 | | Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase | | 著者 | McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L. | | 登録日 | 2015-11-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EXI
 | | Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase | | 著者 | McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L. | | 登録日 | 2015-11-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EXK
 | | Crystal structure of M. tuberculosis lipoyl synthase with 6-thiooctanoyl peptide intermediate | | 分子名称: | 5'-DEOXYADENOSINE, CHLORIDE ION, FE3-S4 CLUSTER, ... | | 著者 | McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L. | | 登録日 | 2015-11-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystallographic snapshots of sulfur insertion by lipoyl synthase.
Proc.Natl.Acad.Sci.USA, 113, 2016
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