5EXK

Crystal structure of M. tuberculosis lipoyl synthase with 6-thiooctanoyl peptide intermediate

Summary for 5EXK

• Entry DOI: 10.2210/pdb5exk/pdb
• Related: 5EXI 5EXJ
• Descriptor: Lipoyl synthase, Octanoylated peptide from M. tuberculosis H protein, FE3-S4 CLUSTER, ... (10 entities in total)
• Functional Keywords: auxiliary iron-sulfur cluster, adomet radical, radical sam, sulfur insertion, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 12
• Total formula weight: 234256.65

Authors

McLaughlin, M.I.,Lanz, N.D.,Goldman, P.J.,Lee, K.-H.,Booker, S.J.,Drennan, C.L. (deposition date: 2015-11-23, release date: 2016-08-10, Last modification date: 2019-11-27)

• Primary citation: McLaughlin, M.I.,Lanz, N.D.,Goldman, P.J.,Lee, K.H.,Booker, S.J.,Drennan, C.L.; Crystallographic snapshots of sulfur insertion by lipoyl synthase.; Proc.Natl.Acad.Sci.USA, 113:9446-9450, 2016; PubMed: 27506792; DOI: 10.1073/pnas.1602486113

Experimental method

X-RAY DIFFRACTION (1.86 Å)