7KDX

Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, and methionine

Summary for 7KDX

Entry DOI	10.2210/pdb7kdx/pdb
Descriptor	Methyltransferase TokK, IRON/SULFUR CLUSTER, 5'-DEOXYADENOSINE, ... (9 entities in total)
Functional Keywords	radical sam, cobalamin, [4fe-4s] cluster, fes cluster, methyltransferase, b12, beta-lactam antibiotic synthesis, transferase
Biological source	Streptomyces tokunonensis
Total number of polymer chains	2
Total formula weight	160534.68
Authors	Knox, H.L.,Booker, S.J.,Boal, A.K. (deposition date: 2020-10-09, release date: 2022-01-12, Last modification date: 2022-02-23)
Primary citation	Knox, H.L.,Sinner, E.K.,Townsend, C.A.,Boal, A.K.,Booker, S.J. Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis. Nature, 602:343-348, 2022 Cited by PubMed: 35110734 DOI: 10.1038/s41586-021-04392-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.791 Å)

Structure validation