6WTF
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound
Summary for 6WTF
Entry DOI | 10.2210/pdb6wtf/pdb |
Related | 6WTE |
Descriptor | Tryptophan-C2-methyltransferase containing B12-binding domain, IRON/SULFUR CLUSTER, COBALAMIN, ... (6 entities in total) |
Functional Keywords | radical sam, cobalamin, fes cluster, methyltransferase, transferase |
Biological source | Kitasatospora setae |
Total number of polymer chains | 2 |
Total formula weight | 132808.52 |
Authors | Knox, H.L.,Chen, P.Y.-T.,Drennan, C.L.,Booker, S.J. (deposition date: 2020-05-02, release date: 2020-12-23, Last modification date: 2023-10-18) |
Primary citation | Knox, H.L.,Chen, P.Y.,Blaszczyk, A.J.,Mukherjee, A.,Grove, T.L.,Schwalm, E.L.,Wang, B.,Drennan, C.L.,Booker, S.J. Structural basis for non-radical catalysis by TsrM, a radical SAM methylase. Nat.Chem.Biol., 17:485-491, 2021 Cited by PubMed: 33462497DOI: 10.1038/s41589-020-00717-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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