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6WTF

Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tryptophan-C2-methyltransferase containing B12-binding domainpolymer57564136.72UniProt (E4N8S5)
Pfam (PF02310)
Pfam (PF04055)
Kitasatospora setae
2C, G
(A, B)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
3D, H
(A, B)
COBALAMINnon-polymer1330.42Chemie (B12)
4E, I
(A, B)
S-5'-AZAMETHIONINE-5'-DEOXYADENOSINEnon-polymer381.42Chemie (SA8)
5F, J
(A, B)
TRYPTOPHANnon-polymer204.22Chemie (TRP)
6K, L
(A, B)
waterwater18.0377Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight128273.3
Non-Polymers*Number of molecules8
Total formula weight4535.2
All*Total formula weight132808.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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