4ZK6
Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States
Summary for 4ZK6
Entry DOI | 10.2210/pdb4zk6/pdb |
Related | 4ZKZ 5FEV 5FFK |
Descriptor | Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (7 entities in total) |
Functional Keywords | quinolicnic acid, biosynthesis of nicotinamide adenine dinucleotide., transferase |
Biological source | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
Total number of polymer chains | 2 |
Total formula weight | 69698.53 |
Authors | Esakova, O.A.,Grove, T.L.,Saunders, A.H.,Yennawar, N.H.,Booker, S.J. (deposition date: 2015-04-29, release date: 2016-06-29, Last modification date: 2023-09-27) |
Primary citation | Esakova, O.A.,Silakov, A.,Grove, T.L.,Saunders, A.H.,McLaughlin, M.I.,Yennawar, N.H.,Booker, S.J. Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid. J.Am.Chem.Soc., 138:7224-7227, 2016 Cited by PubMed: 27224840DOI: 10.1021/jacs.6b02708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.895 Å) |
Structure validation
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