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6OR8

An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase

Summary for 6OR8
Entry DOI10.2210/pdb6or8/pdb
Related4ZK6 4ZKZ 5FEU 5FEV 5FFK
DescriptorQuinolinate synthase A, IRON/SULFUR CLUSTER, 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, ... (5 entities in total)
Functional Keywordsbiosynthesis of nicotinamide adenine dinucleotide, transferase
Biological sourcePyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Total number of polymer chains1
Total formula weight34857.80
Authors
Esakova, O.A.,Grove, T.L.,Yennawar, N.H.,Booker, S.J. (deposition date: 2019-04-29, release date: 2019-10-16, Last modification date: 2023-10-11)
Primary citationEsakova, O.A.,Silakov, A.,Grove, T.L.,Warui, D.M.,Yennawar, N.H.,Booker, S.J.
An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141:14142-14151, 2019
Cited by
PubMed: 31390192
DOI: 10.1021/jacs.9b02513
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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