6NSU

Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States

Summary for 6NSU

Entry DOI	10.2210/pdb6nsu/pdb
Related	4ZK6 4ZKZ 5FEK 5FEU 5FEV 6NSO
Descriptor	Quinolinate synthase A, IRON/SULFUR CLUSTER, DIDEHYDROASPARTATE, ... (4 entities in total)
Functional Keywords	transferase
Biological source	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Total number of polymer chains	1
Total formula weight	34672.75
Authors	Esakova, O.A.,Grove, T.L.,Silakov, A.,Yennawar, N.H.,Booker, S.J. (deposition date: 2019-01-25, release date: 2019-08-21, Last modification date: 2024-03-13)
Primary citation	Esakova, O.A.,Silakov, A.,Grove, T.L.,Warui, D.M.,Yennawar, N.H.,Booker, S.J. An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141:14142-14151, 2019 Cited by PubMed: 31390192 DOI: 10.1021/jacs.9b02513 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation