7S6S
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![BU of 7s6s by Molmil](/molmil-images/mine/7s6s) | Complex structure of Methane monooxygenase hydroxylase and regulatory subunit DBL1 | Descriptor: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | Authors: | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | Deposit date: | 2021-09-14 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics. Biochemistry, 61, 2022
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8STW
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![BU of 8stw by Molmil](/molmil-images/mine/8stw) | K384N HUMAN CYSTATHIONINE BETA-SYNTHASE (delta 411-551) | Descriptor: | Cystathionine beta-synthase, K384N variant, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Mascarenhas, R, Roman, J, Banerjee, R. | Deposit date: | 2023-05-11 | Release date: | 2023-11-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Disease-causing cystathionine beta-synthase linker mutations impair allosteric regulation. J.Biol.Chem., 299, 2023
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1JAC
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![BU of 1jac by Molmil](/molmil-images/mine/1jac) | A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM | Descriptor: | JACALIN, methyl alpha-D-galactopyranoside | Authors: | Sankaranarayanan, R, Sekar, K, Banerjee, R, Sharma, V, Surolia, A, Vijayan, M. | Deposit date: | 1996-05-22 | Release date: | 1997-06-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a beta-prism fold. Nat.Struct.Biol., 3, 1996
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3BT8
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![BU of 3bt8 by Molmil](/molmil-images/mine/3bt8) | |
4A91
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![BU of 4a91 by Molmil](/molmil-images/mine/4a91) | Crystal structure of the glutamyl-queuosine tRNAAsp synthetase from E. coli complexed with L-glutamate | Descriptor: | GLUTAMIC ACID, GLUTAMYL-Q TRNA(ASP) SYNTHETASE, ZINC ION | Authors: | Blaise, M, Olieric, V, Sauter, C, Lorber, B, Roy, B, Karmakar, S, Banerjee, R, Becker, H.D, Kern, D. | Deposit date: | 2011-11-22 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Glutamyl-Queuosine Trnaasp Synthetase Complexed with L-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of Trnaasp Anticodon. J.Mol.Biol., 381, 2008
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2HAQ
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![BU of 2haq by Molmil](/molmil-images/mine/2haq) | Crystal Structure of Cyclophilin A from Leishmania Donovani | Descriptor: | Cyclophilin | Authors: | Venugopal, V, Sen, B, Datta, A.K, Banerjee, R. | Deposit date: | 2006-06-13 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of cyclophilin from Leishmania donovani at 1.97 A resolution. Acta Crystallogr.,Sect.F, 63, 2007
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8DHK
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![BU of 8dhk by Molmil](/molmil-images/mine/8dhk) | |
8DYJ
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![BU of 8dyj by Molmil](/molmil-images/mine/8dyj) | Crystal structure of human methylmalonyl-CoA mutase in complex with ADP and cob(II)alamin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, COBALAMIN, Methylmalonyl-CoA mutase, ... | Authors: | Mascarenhas, R.N, Gouda, H, Banerjee, R. | Deposit date: | 2022-08-04 | Release date: | 2023-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DYL
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![BU of 8dyl by Molmil](/molmil-images/mine/8dyl) | Crystal structure of human methylmalonyl-CoA mutase bound to aquocobalamin | Descriptor: | COBALAMIN, GLYCEROL, Methylmalonyl-CoA mutase, ... | Authors: | Mascarenhas, R.N, Gouda, H, Banerjee, R. | Deposit date: | 2022-08-04 | Release date: | 2023-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair. Proc.Natl.Acad.Sci.USA, 120, 2023
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8D32
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![BU of 8d32 by Molmil](/molmil-images/mine/8d32) | Mycobacterium tuberculosis pduO-type ATP:cobalamin adenosyltransferase bound to 5-deoxyadenosylrhodibalamin and PPPi | Descriptor: | 5'-DEOXYADENOSINE, Corrinoid adenosyltransferase, MAGNESIUM ION, ... | Authors: | Mascarenhas, R.N, Ruetz, M, Koutmos, M, Banerjee, R. | Deposit date: | 2022-05-31 | Release date: | 2023-05-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A noble substitution leads to the cofactor mimicry by rhodibalamin To Be Published
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1M54
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![BU of 1m54 by Molmil](/molmil-images/mine/1m54) | CYSTATHIONINE-BETA SYNTHASE: REDUCED VICINAL THIOLS | Descriptor: | CYSTATHIONINE BETA-SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Taoka, S, Lepore, B.W, Kabil, O, Ojha, S, Ringe, D, Banerjee, R. | Deposit date: | 2002-07-08 | Release date: | 2002-08-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | HUMAN CYSTATHIONINE BETA-SYNTHASE IS A HEME SENSOR PROTEIN. EVIDENCE THAT THE
REDOX SENSOR IS HEME AND NOT THE VICINAL CYSTEINES IN THE CXXC MOTIF SEEN IN THE CRYSTAL STRUCTURE OF THE TRUNCATED ENZYME BIOCHEMISTRY, 41, 2002
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3EOV
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![BU of 3eov by Molmil](/molmil-images/mine/3eov) | Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A | Descriptor: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | Authors: | Venugopal, V, Dasgupta, D, Datta, A.K, Banerjee, R. | Deposit date: | 2008-09-29 | Release date: | 2008-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data. Acta Crystallogr.,Sect.D, 65, 2009
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8GJU
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![BU of 8gju by Molmil](/molmil-images/mine/8gju) | Crystal structure of human methylmalonyl-CoA mutase (MMUT) in complex with methylmalonic acidemia type A protein (MMAA), coenzyme A, and GDP | Descriptor: | COENZYME A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mascarenhas, R.M, Ruetz, M, Gouda, H, Yaw, M, Banerjee, R. | Deposit date: | 2023-03-16 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair. Nat Commun, 14, 2023
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8HQC
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![BU of 8hqc by Molmil](/molmil-images/mine/8hqc) | Structure of a GPCR-G protein in complex with a natural peptide agonist | Descriptor: | Antibody fragment, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Saha, S, Maharana, J, Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-12-13 | Release date: | 2023-10-18 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8HPT
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![BU of 8hpt by Molmil](/molmil-images/mine/8hpt) | Structure of C5a-pep bound mouse C5aR1 in complex with Go | Descriptor: | Antibody fragment ScFv16, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Saha, S, Maharana, J, Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-12-13 | Release date: | 2023-10-18 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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6L2B
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![BU of 6l2b by Molmil](/molmil-images/mine/6l2b) | |
6OXC
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![BU of 6oxc by Molmil](/molmil-images/mine/6oxc) | Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, Methylmalonyl-CoA mutase large subunit, ... | Authors: | Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M. | Deposit date: | 2019-05-13 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science, 366, 2019
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8GO8
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![BU of 8go8 by Molmil](/molmil-images/mine/8go8) | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 | Descriptor: | Beta-arrestin-1, C5a anaphylatoxin chemotactic receptor 1, Fab30 heavy chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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8GOO
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![BU of 8goo by Molmil](/molmil-images/mine/8goo) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 | Descriptor: | Beta-arrestin-2, C5a anaphylatoxin chemotactic receptor 1, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-25 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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5CV0
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![BU of 5cv0 by Molmil](/molmil-images/mine/5cv0) | Crystal structure of N-terminal truncated human B12-chaperone CblD (108-296) | Descriptor: | Methylmalonic aciduria and homocystinuria type D protein, mitochondrial | Authors: | Yamada, K, Gherasim, C, Banerjee, R, Koutmos, M. | Deposit date: | 2015-07-24 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Human B12 Trafficking Protein CblD Reveals Molecular Mimicry and Identifies a New Subfamily of Nitro-FMN Reductases. J.Biol.Chem., 290, 2015
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5CUZ
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![BU of 5cuz by Molmil](/molmil-images/mine/5cuz) | Crystal structure of SeMet-substituted N-terminal truncated human B12-chaperone CblD (108-296) | Descriptor: | Methylmalonic aciduria and homocystinuria type D protein, mitochondrial | Authors: | Yamada, K, Gherasim, C, Banerjee, R, Koutmos, M. | Deposit date: | 2015-07-25 | Release date: | 2015-09-23 | Last modified: | 2015-12-16 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structure of Human B12 Trafficking Protein CblD Reveals Molecular Mimicry and Identifies a New Subfamily of Nitro-FMN Reductases. J.Biol.Chem., 290, 2015
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8GOC
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![BU of 8goc by Molmil](/molmil-images/mine/8goc) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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8GP3
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![BU of 8gp3 by Molmil](/molmil-images/mine/8gp3) | Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 | Descriptor: | Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-25 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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6NBA
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![BU of 6nba by Molmil](/molmil-images/mine/6nba) | Crystal structure of Human Cystathionine gamma lyase with S-3-Carboxpropyl-L-Cysteine | Descriptor: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine gamma-lyase | Authors: | Kim, H, Yadav, P.K, Banerjee, R, Cho, U.-S. | Deposit date: | 2018-12-06 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine gamma-lyase-dependent hydrogen sulfide synthesis. J.Biol.Chem., 294, 2019
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6OXD
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![BU of 6oxd by Molmil](/molmil-images/mine/6oxd) | Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, Itaconyl coenzyme A, ... | Authors: | Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M. | Deposit date: | 2019-05-13 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair. Science, 366, 2019
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