8GP3

Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4

Summary for 8GP3

Entry DOI	10.2210/pdb8gp3/pdb
EMDB information	34188
Descriptor	Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ... (4 entities in total)
Functional Keywords	gpcr, arrestin, signaling protein
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	8
Total formula weight	196832.91
Authors	Maharana, J.,Sarma, P.,Yadav, M.K.,Banerjee, R.,Shukla, A.K. (deposition date: 2022-08-25, release date: 2023-05-17, Last modification date: 2024-07-17)
Primary citation	Maharana, J.,Sarma, P.,Yadav, M.K.,Saha, S.,Singh, V.,Saha, S.,Chami, M.,Banerjee, R.,Shukla, A.K. Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83:2091-2107.e7, 2023 Cited by PubMed: 37209686 DOI: 10.1016/j.molcel.2023.04.025 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.8 Å)

Structure validation