8D32

Mycobacterium tuberculosis pduO-type ATP:cobalamin adenosyltransferase bound to 5-deoxyadenosylrhodibalamin and PPPi

Summary for 8D32

• Entry DOI: 10.2210/pdb8d32/pdb
• Descriptor: Corrinoid adenosyltransferase, [5-(5,6-dimethyl-1H-benzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl 1-{3-[3,14,19-tris(2-amino-2-oxoethyl)-8,13,18-tris(3-amino-3-oxopropyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1~2,5~.1~7,10~.1~12,15~]tricosa-5(23),6,10,12(21),15,17(20)-hexaen-4-yl-kappa~4~N~20~,N~21~,N~22~,N~23~]propanamido}propan-2-yl hydrogenato phosphate]rhodium (non-preferred name), 5'-DEOXYADENOSINE, ... (6 entities in total)
• Functional Keywords: chaperone, b12 trafficking, transferase, rhodium
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 22650.51

Authors

Mascarenhas, R.N.,Ruetz, M.,Koutmos, M.,Banerjee, R. (deposition date: 2022-05-31, release date: 2023-05-10, Last modification date: 2023-10-25)

• Primary citation: Ruetz, M.,Mascarenhas, R.N.,Koutmos, M.,Krautler, B.,Banerjee, R.; A noble substitution leads to the cofactor mimicry by rhodibalamin; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)