8HQC
Structure of a GPCR-G protein in complex with a natural peptide agonist
Summary for 8HQC
Entry DOI | 10.2210/pdb8hqc/pdb |
EMDB information | 34947 |
Descriptor | C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, g protein, signaling protein, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 154007.55 |
Authors | Saha, S.,Maharana, J.,Yadav, M.K.,Sarma, P.,Chami, M.,Banerjee, R.,Shukla, A.K. (deposition date: 2022-12-13, release date: 2023-10-18, Last modification date: 2024-07-17) |
Primary citation | Yadav, M.K.,Maharana, J.,Yadav, R.,Saha, S.,Sarma, P.,Soni, C.,Singh, V.,Saha, S.,Ganguly, M.,Li, X.X.,Mohapatra, S.,Mishra, S.,Khant, H.A.,Chami, M.,Woodruff, T.M.,Banerjee, R.,Shukla, A.K.,Gati, C. Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186:4956-4973.e21, 2023 Cited by PubMed: 37852260DOI: 10.1016/j.cell.2023.09.020 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.89 Å) |
Structure validation
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