1M54
CYSTATHIONINE-BETA SYNTHASE: REDUCED VICINAL THIOLS
Summary for 1M54
Entry DOI | 10.2210/pdb1m54/pdb |
Related | 1JBQ |
Descriptor | CYSTATHIONINE BETA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | plp protein fold type ii (tryptophan synthase), plp and heme bound to protein, reduced vicinal cysteines, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P35520 |
Total number of polymer chains | 6 |
Total formula weight | 244718.14 |
Authors | Taoka, S.,Lepore, B.W.,Kabil, O.,Ojha, S.,Ringe, D.,Banerjee, R. (deposition date: 2002-07-08, release date: 2002-08-14, Last modification date: 2021-10-27) |
Primary citation | Taoka, S.,Lepore, B.W.,Kabil, O.,Ojha, S.,Ringe, D.,Banerjee, R. HUMAN CYSTATHIONINE BETA-SYNTHASE IS A HEME SENSOR PROTEIN. EVIDENCE THAT THE REDOX SENSOR IS HEME AND NOT THE VICINAL CYSTEINES IN THE CXXC MOTIF SEEN IN THE CRYSTAL STRUCTURE OF THE TRUNCATED ENZYME BIOCHEMISTRY, 41:10454-10461, 2002 Cited by PubMed: 12173932DOI: 10.1021/bi026052d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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