8DYJ

Crystal structure of human methylmalonyl-CoA mutase in complex with ADP and cob(II)alamin

Summary for 8DYJ

Entry DOI	10.2210/pdb8dyj/pdb
Descriptor	Methylmalonyl-CoA mutase, mitochondrial, COBALAMIN, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	cobalamin, adp, mutase, vitamin b12, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	86593.38
Authors	Mascarenhas, R.N.,Gouda, H.,Banerjee, R. (deposition date: 2022-08-04, release date: 2023-07-12, Last modification date: 2023-10-25)
Primary citation	Gouda, H.,Mascarenhas, R.,Ruetz, M.,Yaw, M.,Banerjee, R. Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair. Proc.Natl.Acad.Sci.USA, 120:e2220677120-e2220677120, 2023 Cited by PubMed: 36888659 DOI: 10.1073/pnas.2220677120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation