8GO8

Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1

Summary for 8GO8

• Entry DOI: 10.2210/pdb8go8/pdb
• EMDB information: 34173
• Descriptor: Beta-arrestin-1, C5a anaphylatoxin chemotactic receptor 1, Fab30 heavy chain, ... (4 entities in total)
• Functional Keywords: gpcr, arrestin, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 8
• Total formula weight: 197468.53

Authors

Maharana, J.,Sarma, P.,Yadav, M.K.,Banerjee, R.,Shukla, A.K. (deposition date: 2022-08-24, release date: 2023-05-17, Last modification date: 2024-07-17)

• Primary citation: Maharana, J.,Sarma, P.,Yadav, M.K.,Saha, S.,Singh, V.,Saha, S.,Chami, M.,Banerjee, R.,Shukla, A.K.; Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation.; Mol.Cell, 83:2091-2107.e7, 2023; PubMed: 37209686; DOI: 10.1016/j.molcel.2023.04.025

Experimental method

ELECTRON MICROSCOPY (3.41 Å)