8STW

K384N HUMAN CYSTATHIONINE BETA-SYNTHASE (delta 411-551)

Summary for 8STW

Entry DOI	10.2210/pdb8stw/pdb
Descriptor	Cystathionine beta-synthase, K384N variant, PYRIDOXAL-5'-PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	plp, heme, hydrogen sulfide, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	244627.66
Authors	Mascarenhas, R.,Roman, J.,Banerjee, R. (deposition date: 2023-05-11, release date: 2023-11-22, Last modification date: 2023-12-20)
Primary citation	Roman, J.V.,Mascarenhas, R.,Ceric, K.,Ballou, D.P.,Banerjee, R. Disease-causing cystathionine beta-synthase linker mutations impair allosteric regulation. J.Biol.Chem., 299:105449-105449, 2023 Cited by PubMed: 37949228 DOI: 10.1016/j.jbc.2023.105449 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation