6NBA

Crystal structure of Human Cystathionine gamma lyase with S-3-Carboxpropyl-L-Cysteine

Summary for 6NBA

• Entry DOI: 10.2210/pdb6nba/pdb
• Descriptor: Cystathionine gamma-lyase, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID (3 entities in total)
• Functional Keywords: lyase, complex
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 178267.24

Authors

Kim, H.,Yadav, P.K.,Banerjee, R.,Cho, U.-S. (deposition date: 2018-12-06, release date: 2019-06-12, Last modification date: 2023-10-11)

• Primary citation: Yadav, P.K.,Vitvitsky, V.,Kim, H.,White, A.,Cho, U.S.,Banerjee, R.; S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine gamma-lyase-dependent hydrogen sulfide synthesis.; J.Biol.Chem., 294:11011-11022, 2019; PubMed: 31160338; DOI: 10.1074/jbc.RA119.009047

Experimental method

X-RAY DIFFRACTION (2.495 Å)