3Q2M
| Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, Protein Kinase Inhibitor CKI-7 Complex | 分子名称: | N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, NICKEL (II) ION, Spectinomycin phosphotransferase | 著者 | Berghuis, A.M, Fong, D.H, Xiong, B, Hwang, J. | 登録日 | 2010-12-20 | 公開日 | 2011-05-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6, 2011
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2GF9
| Crystal structure of human RAB3D in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-3D, ... | 著者 | Hong, B, Wang, J, Shen, L, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-03-21 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structure of human RAB3D in complex with GDP To be Published
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2FXZ
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6KVS
| Staphylococcus aureus FabH with covalent inhibitor Oxa1 | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, 4-chloranyl-N-[[cyclopropylmethyl(methanoyl)amino]methyl]benzamide | 著者 | Yuan, Y, Wang, J. | 登録日 | 2019-09-05 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase To Be Published
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4NPP
| The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms | 分子名称: | NICKEL (II) ION, Proton-gated ion channel | 著者 | Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M. | 登録日 | 2013-11-22 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111, 2014
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2HEI
| Crystal structure of human RAB5B in complex with GDP | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-5B | 著者 | Hong, B, Shen, L, Wang, J, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-06-21 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of human RAB5B in complex with GDP To be Published
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2II4
| Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form | 分子名称: | CHLORIDE ION, COENZYME A, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | 登録日 | 2006-09-27 | 公開日 | 2006-12-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
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2II3
| Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form | 分子名称: | ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | 登録日 | 2006-09-27 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
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1HF9
| C-Terminal Coiled-Coil Domain from Bovine IF1 | 分子名称: | ATPASE INHIBITOR (MITOCHONDRIAL) | 著者 | Gordon-Smith, D.J, Carbajo, R.J, Yang, J.-C, Videler, H, Runswick, M.J, Walker, J.E, Neuhaus, D. | 登録日 | 2000-11-30 | 公開日 | 2001-05-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase. J. Mol. Biol., 308, 2001
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1IC1
| THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, INTERCELLULAR ADHESION MOLECULE-1 | 著者 | Casasnovas, J.M, Stehle, T, Liu, J.-H, Wang, J.-H, Springer, T.A. | 登録日 | 1998-03-09 | 公開日 | 1998-06-17 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proc.Natl.Acad.Sci.USA, 95, 1998
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4NK7
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1OXZ
| Crystal Structure of the Human GGA1 GAT domain | 分子名称: | ADP-ribosylation factor binding protein GGA1 | 著者 | Zhu, G, Zhai, P, He, X, Terzyan, S, Zhang, R, Joachimiak, A, Tang, J, Zhang, X.C. | 登録日 | 2003-04-03 | 公開日 | 2003-04-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Human GGA1 GAT Domain Biochemistry, 42, 2003
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2VRL
| Structure of human MAO B in complex with benzylhydrazine | 分子名称: | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, TOLUENE | 著者 | Binda, C, Wang, J, Li, M, Hubalek, F, Mattevi, A, Edmondson, D.E. | 登録日 | 2008-04-09 | 公開日 | 2008-04-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B Biochemistry, 47, 2008
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1NMI
| Solution structure of the imidazole complex of iso-1 cytochrome c | 分子名称: | Cytochrome c, iso-1, HEME C, ... | 著者 | Yao, Y, Tong, Y, Liu, G, Wang, J, Zheng, J, Tang, W. | 登録日 | 2003-01-10 | 公開日 | 2003-02-04 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the imidazole complex of iso-1 cytochrome c To be Published
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2II5
| Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Isobutyryl-Coenzyme A-bound form | 分子名称: | ACETATE ION, CHLORIDE ION, ISOBUTYRYL-COENZYME A, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | 登録日 | 2006-09-27 | 公開日 | 2006-12-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
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2VRM
| Structure of human MAO B in complex with phenyethylhydrazine | 分子名称: | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, PHENYLETHANE | 著者 | Binda, C, Wang, J, Li, M, Hubalek, F, Mattevi, A, Edmondson, D.E. | 登録日 | 2008-04-09 | 公開日 | 2008-04-22 | 最終更新日 | 2014-01-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B Biochemistry, 47, 2008
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2IHW
| Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form | 分子名称: | ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | 登録日 | 2006-09-27 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
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1NY8
| Solution structure of Protein yrbA from Escherichia Coli: Northeast Structural Genomics Consortium target ER115 | 分子名称: | Protein yrbA | 著者 | Swapna, G.V.T, Huang, J.Y, Acton, T.B, Shastry, R, Chiang, Y.-W, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-02-11 | 公開日 | 2004-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Protein yrbA from Escherichia Coli: Northeast Structural Genomics Consortium target ER115 To be Published
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4QAC
| X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(4-methylpiperidin-1-yl)-6-(4-(trifluoromethyl)phenyl)pyrimidin-2-amine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(4-methylpiperidin-1-yl)-6-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine, Acetylcholine-binding protein, ... | 著者 | Kaczanowska, K, Harel, M, Radic, Z, Changeux, J.-P, Finn, M.G, Taylor, P. | 登録日 | 2014-05-03 | 公開日 | 2014-07-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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2J9F
| Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase E1b | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-PROPYL-THIAMIN DIPHOSPHATE, ... | 著者 | Jun, L, Machius, M, Chuang, J.L, Wynn, R.M, Chuang, D.T. | 登録日 | 2006-11-07 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | The Two Active Sites in Human Branched-Chain Alpha- Keto Acid Dehydrogenase Operate Independently without an Obligatory Alternating-Site Mechanism. J.Biol.Chem., 282, 2007
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2ZKJ
| Crystal structure of human PDK4-ADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Li, J, Chuang, D.T. | 登録日 | 2008-03-25 | 公開日 | 2008-08-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity J.Biol.Chem., 283, 2008
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4BK0
| Crystal structure of the KIX domain of human RECQL5 (domain-swapped dimer) | 分子名称: | ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER | 著者 | Kassube, S.A, Jinek, M, Fang, J, Tsutakawa, S, Nogales, E. | 登録日 | 2013-04-21 | 公開日 | 2013-06-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5 Nat.Struct.Mol.Biol., 20, 2013
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4QAA
| X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(4-Methoxyphenyl)-N4-octylpyrimidine-2,4-diamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(4-methoxyphenyl)-N~4~-octylpyrimidine-2,4-diamine, Acetylcholine-binding protein, ... | 著者 | Kaczanowska, K, Harel, M, Radic, Z, Changeux, J.-P, Finn, M.G, Taylor, P. | 登録日 | 2014-05-03 | 公開日 | 2014-07-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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2B5G
| Wild Type SSAT- 1.7A structure | 分子名称: | Diamine acetyltransferase 1, SULFATE ION | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2005-09-28 | 公開日 | 2006-01-17 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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1FKN
| Structure of Beta-Secretase Complexed with Inhibitor | 分子名称: | MEMAPSIN 2, inhibitor | 著者 | Hong, L, Koelsch, G, Lin, X, Wu, S, Terzyan, S, Ghosh, A, Zhang, X.C, Tang, J. | 登録日 | 2000-08-09 | 公開日 | 2000-10-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science, 290, 2000
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