4QAA

X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(4-Methoxyphenyl)-N4-octylpyrimidine-2,4-diamine

Summary for 4QAA

• Entry DOI: 10.2210/pdb4qaa/pdb
• Related: 1UV6 1UW6 1UX2 4QAB 4QAC
• Descriptor: Acetylcholine-binding protein, 6-(4-methoxyphenyl)-N~4~-octylpyrimidine-2,4-diamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: acetylcholine-binding protein
• Biological source: Lymnaea stagnalis (Great pond snail)
• Cellular location: Secreted: P58154
• Total number of polymer chains: 10
• Total formula weight: 254764.43

Authors

Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.-P.,Finn, M.G.,Taylor, P. (deposition date: 2014-05-03, release date: 2014-07-16, Last modification date: 2020-07-29)

• Primary citation: Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.P.,Finn, M.G.,Taylor, P.; Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein.; Proc.Natl.Acad.Sci.USA, 111:10749-10754, 2014; PubMed: 25006260; DOI: 10.1073/pnas.1410992111

Experimental method

X-RAY DIFFRACTION (2.7 Å)