2J9F
Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase E1b
Summary for 2J9F
Entry DOI | 10.2210/pdb2j9f/pdb |
Related | 1DTW 1OLS 1OLU 1OLX 1U5B 1V11 1V16 1V1M 1V1R 1WCI 1X7W 1X7X 1X7Y 1X7Z 1X80 2BEU 2BEV 2BEW 2BFB 2BFC 2BFD 2BFE 2BFF |
Descriptor | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, MANGANESE (II) ION, ... (7 entities in total) |
Functional Keywords | oxidoreductase, flavoprotein, mitochondrion, thiamine pyrophosphate, maple syrup urine disease, transit peptide, phosphorylation, disease mutation, metal-binding, multi-enzyme complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 170388.12 |
Authors | Jun, L.,Machius, M.,Chuang, J.L.,Wynn, R.M.,Chuang, D.T. (deposition date: 2006-11-07, release date: 2007-02-27, Last modification date: 2023-12-13) |
Primary citation | Li, J.,Machius, M.,Chuang, J.L.,Wynn, R.M.,Chuang, D.T. The Two Active Sites in Human Branched-Chain Alpha- Keto Acid Dehydrogenase Operate Independently without an Obligatory Alternating-Site Mechanism. J.Biol.Chem., 282:11904-, 2007 Cited by PubMed: 17329260DOI: 10.1074/JBC.M610843200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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