4NPP
The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms
Summary for 4NPP
Entry DOI | 10.2210/pdb4npp/pdb |
Related | 4NPQ |
Descriptor | Proton-gated ion channel, NICKEL (II) ION (2 entities in total) |
Functional Keywords | pentameric ligand-gated ion channel, ph-gated, transmembrane, transport protein |
Biological source | Gloeobacter violaceus |
Cellular location | Cell inner membrane ; Multi- pass membrane protein : Q7NDN8 |
Total number of polymer chains | 5 |
Total formula weight | 189229.99 |
Authors | Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M. (deposition date: 2013-11-22, release date: 2013-12-25, Last modification date: 2023-09-20) |
Primary citation | Sauguet, L.,Shahsavar, A.,Poitevin, F.,Huon, C.,Menny, A.,Nemecz, A.,Haouz, A.,Changeux, J.P.,Corringer, P.J.,Delarue, M. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111:966-971, 2014 Cited by PubMed: 24367074DOI: 10.1073/pnas.1314997111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
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