2IHW
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form
Summary for 2IHW
| Entry DOI | 10.2210/pdb2ihw/pdb |
| Related | 2II3 2II4 2II5 |
| Descriptor | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ACETATE ION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | cubic core, homo trimer, apo form, transferase |
| Biological source | Bos taurus (cattle) |
| Cellular location | Mitochondrion matrix : P11181 |
| Total number of polymer chains | 8 |
| Total formula weight | 231182.75 |
| Authors | Kato, M.,Wynn, R.M.,Chuang, J.L.,Brautigam, C.A.,Custorio, M.,Chuang, D.T. (deposition date: 2006-09-27, release date: 2006-12-26, Last modification date: 2023-08-30) |
| Primary citation | Kato, M.,Wynn, R.M.,Chuang, J.L.,Brautigam, C.A.,Custorio, M.,Chuang, D.T. A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25:5983-5994, 2006 Cited by PubMed: 17124494DOI: 10.1038/sj.emboj.7601444 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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